Results 121 to 130 of about 595,672 (312)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Predictive value of serum uric acid in hospitalized adolescents and adults with acute asthma [PDF]

open access: yes, 2016
Nasser Keshar Abdulnaby,1 Ashraf Othman Sayed,2 Nehad Mohamed Shalaby3 1Chest Diseases and Tuberculosis Department, Faculty of Medicine, Cairo University, Cairo, 2Department of Pediatrics, Children and Women’s University Hospital, Minia University,
Sayed AO, Abdulnaby NK, Shalaby NM
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Executive Stock Option Exercises and the Predictive Ability of Transaction Value [PDF]

open access: yes, 2004
This paper investigates the predictive ability of executives’ stock option exercises by categorising all exercises by the overall value of the transaction. This measure incorporates the cost to the executive of exercising the option, together with the
Mase, B, Kyriacou, K
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Understanding stock return predictability [PDF]

open access: yes
Over the period 1927:Q1 to 2005:Q4, the average CAPM-based idiosyncratic variance (IV) and stock market variance jointly forecast stock market returns.
Hui Guo, Robert Savickas
core  

Predictive value of allergy tests for neuromuscular blocking agents : tackling an unmet need [PDF]

open access: yes, 2014
: Background Neuromuscular blocking agents (NMBAs) are a predominant cause of perioperative anaphylaxis in Europe. Diagnosis of NMBA allergy relies upon the careful review of the anaesthetic report complemented with skin tests.
Uyttebroek, Astrid   +5 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The Predictive Value of Preoperative Systemic Immune-Inflammation Index in Patients with Granulomatous Mastitis [PDF]

open access: yes
Liquan Ouyang,1 Jieting Qin,2 Tianyue Cui,1 Yuyan Tan1 1Department of Thyroid and Breast Surgery, The First College of Clinical Medical Science, China Three Gorges University, Yichang, 443022, People’s Republic of China; 2Department of Cardiology ...
Qin J, Tan Y, Ouyang L, Cui T
core   +1 more source

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