Verification of the Utility of Urinary L-FABP as a Predictor of Impaired Renal Function Based on Its Relationship with Changes in Renal Function. [PDF]
J Clin MedKato Y, Sugaya T.
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Using machine learning to predict the small for gestational age and identify the important predictors: A real-world clinical cohort study in China. [PDF]
PLoS OneZhang Y, Liu Z, Liu J, Chen J, Zhang X.
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Gene-specific pathogenicity predictor for chromatin remodeling BAF complex-associated neurodevelopmental disorders. [PDF]
HGG AdvHack J, Nazim M.
europepmc +1 more source
Self-rated health: a predictor of mortality among the elderly.
American Journal of Public Health, 1982 J. Mossey, E. Shapiro
semanticscholar +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Who's at risk for emergent depression years later? Predictive modeling in a nine-year longitudinal cohort. [PDF]
BMC PsychiatryZainal NH +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Influence of Chronological Age, Anthropometric Characteristics and Biological Maturity on Eccentric Knee Flexion Strength During the Nordic Hamstring Exercise in Female International Youth Soccer Players. [PDF]
Eur J Sport SciHickey JT +4 more
europepmc +1 more source