Results 81 to 90 of about 8,804,924 (318)

Yeah, Right, Uh-Huh: A Deep Learning Backchannel Predictor

, 2017
Using supporting backchannel (BC) cues can make human-computer interaction more social. BCs provide a feedback from the listener to the speaker indicating to the speaker that he is still listened to.
A Stolcke, A Waibel, J Niehues, K Laskowski, M Schroder, N Srivastava, N Ward, X Glorot   +7 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Predictor Role of VKORC1 rs9923231, CYP4F2 rs2108622, and GGCX rs11676382 Polymorphisms of 5 Years Mortality of Patients with Acute Ischemic Stroke

Medicina
Background and Objectives: The aim of this study was to evaluate the potential predictive value of VKORC1, CYP4F2, and GGCX polymorphisms, as well as other clinical and demographic factors, for 5-year mortality in patients with acute ischemic stroke (AIS)
Silvina Iluţ, Valer Donca, Antonia Eugenia Macarie, Ştefan Cristian Vesa, Raluca Maria Pop, Vitalie Văcăraş, Diana Şipoş-Lascu, Ioana Cristina Bârsan, Lăcrămioara Perju-Dumbravă, Ovidiu Sorin Chiroban, Camelia Alexandra Coadă, Anca Dana Buzoianu   +11 more
doaj   +1 more source

Digital phase-lock loop having an estimator and predictor of error [PDF]

, 1988
A digital phase-lock loop (DPLL) which generates a signal with a phase that approximates the phase of a received signal with a linear estimator. The effect of a complication associated with non-zero transport delays related to DPLL mechanization is then ...
Hurd, William J., Statman, Joseph I.
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Accurate DNA methylation predictor for C9orf72 repeat expansion alleles in the pathogenic range

HGG Advances
Summary: The hexanucleotide (G4C2) repeat expansion in the promoter region of C9orf72 is the most frequent genetic cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).
Naren Ramesh, Alexandria Evans, Kevin Wojta, Zhongan Yang, Marco P. Boks, René S. Kahn, Sterre C.M. de Boer, Sven J. van der Lee, Yolande A.L. Pijnenburg, Lianne M. Reus, Roel A. Ophoff   +10 more
doaj   +1 more source

Clinical Predictors of High Blood Eosinophils in Chronic Obstructive Pulmonary Disease

International Journal of COPD, 2021
Mei Yang,* Ting Yang,* Xiaoou Li,* Diandian Li, Zenglin Liao, Yongchun Shen, Dan Xu, Lei Chen, Fuqiang Wen Department of Respiratory and Critical Care Medicine, West China Hospital, West China School of Medicine, Sichuan University, Chengdu ...
Yang M, Yang T, Li X, Li D, Liao Z, Shen Y, Xu D, Chen L, Wen F   +8 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

First Trimester Vaginal Microbiome as Pregnancy Outcome Predictor [PDF]

, 2016
• We have developed clinical definiKons of healthy and complicated pregnancies based on pathologies that will be used in future VaHMP studies. • Although one study7 found dysbioKc vagitypes in all three semesters of women who had PPROM, none of our PPROM
Fettwis, Jennifer M., Rozycki, Sarah K.
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source