Results 41 to 50 of about 2,674,866 (251)

Killing Glioblastoma Cells with Glycosylated Indolocarbazole-Based Derivative LCS1269: A Potential Crosstalk Between Micronuclei Formation and the Concurrent Induction of Apoptosis, Necroptosis, and Pyroptosis

Pharmaceuticals
Background/Objectives: Glioblastoma multiforme (GBM) is the most infiltrative, treatment-resistant, and deadly brain tumor in adults. Given the extremely malignant phenotype of the GBM cells, the high intratumoral heterogeneity, and the limited efficacy ...
Nikolay Kalitin, Alexander Masyutin, Maria Erokhina, Ekaterina Savchenko, Nadezhda Samoylenkova, Aida Karamysheva, Galina Pavlova   +6 more
doaj   +1 more source

Penalized Regression with Ordinal Predictors [PDF]

, 2008
Ordered categorial predictors are a common case in regression modeling. In contrast to the case of ordinal response variables, ordinal predictors have been largely neglected in the literature. In this article penalized regression techniques are proposed.
Gertheiss, Jan, Tutz, Gerhard
core   +1 more source

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim, Natalie Bradford, David Brain, Sameera Senanayake, Sanjeewa Kularatna, Kate Young, Christine Cashion, Tim Hassall, Susanna Cramb   +8 more
wiley   +1 more source

The Sudden Cardiac Death Continuum. Message 2

Неотложная медицинская помощь
INTRODUCTION. The study of the disease, including sudden cardiac death (SCD), as a consistent pathological process makes it possible to discover its mechanisms of formation, progression, and determine methods of prediction and prevention.AIM OF THE STUDY.
A. Yu. Lazutkina
doaj   +1 more source

Predictors of COVID-19 severity among pregnant patients

Biomolecules & Biomedicine, 2022
Coronavirus disease 2019 (COVID-19) was declared a pandemic and has spread around the globe, unsparingly affecting vulnerable populations. Effective prevention measures for pregnant women, who are particularly affected, include early identification of ...
Marcin Januszewski, Laura Ziuzia-Januszewska, Alicja A. Jakimiuk, Tomasz Oleksik, Marek Pokulniewicz, Waldemar Wierzba, Krzysztof Kozlowski, Artur J. Jakimiuk   +7 more
doaj   +1 more source

Multidimensional screening for predicting pain problems in adults : a systematic review of screening tools and validation studies [PDF]

, 2019
Screening tools allowing to predict poor pain outcomes are widely used. Often these screening tools contain psychosocial risk factors. This review (1) identifies multidimensional screening tools that include psychosocial risk factors for the development ...
Abegglen, Althof, Andersen, Austin, Beneciuk, Blyth, Breivik, Broadbent, Cella, Chiarotto, Chiarotto, Collins, Crombez, Dagfinrud, Debray, Debray, den Boer, Dunstan, Eccleston, Field, Foster, Fritz, Gabel, Gabel, Gabel, Gatchel, Gatchel, George, George, Gray, Grotle, Grotle, Grotle, Gureje, Hahn, Hayden, Hayden, Heneweer, Henschke, Hill, Hockings, Hurley, Hurley, Iles, Janssen, Justice, Kalkman, Karran, Karran, Khan, Kongsted, Lang, Law, Lee, Leeuw, Lentz, Leysen, Linton, Linton, Linton, Linton, Maher, Main, Margison, Marhold, Melloh, Miller, Moerman, Moher, Montori, Moons, Moons, Moons, Moons, Morsø, Morsø, Neubauer, Newell, Nonclercq, Pajouheshnia, Pajouheshnia, Peat, Peduzzi, Pengel, Phillips, Pincus, Porter, Ramond, Riewe, Rodeghero, Royston, Saastamoinen, Sandborgh, Sandborgh, Sattelmayer, Schultz, Scott, Shahidi, Shaw, Shaw, Shaw, Sobol-Kwapinska, Steenstra, Steyerberg, Steyerberg, Steyerberg, Streibelt, Sullivan, Toth, Traeger, Truchon, Tu, Tucker, Tucker, Vickers, Vickers, Vlaeyen, Vlaeyen, Vos, Walton, Wingbermuhle, Wolff, Wolff   +122 more
core   +2 more sources

Hospital length of stay and its predictors among surgical patients at public hospitals in Addis Ababa, Ethiopia

Frontiers in Surgery
BackgroundReducing the length of hospital stay can significantly lower healthcare costs, minimize the risk of hospital-acquired infections and complications, and improve patient well-being.
Samuel Dessu Sifer, Abduselam Ahmed Abdela, Milkiyas Solomon Getachew, Redait Awoke Assefa, Abatalem Minlargeh Abere   +4 more
doaj   +1 more source

A note on between-group PCA [PDF]

, 2004
In the context of binary classification with continuous predictors, we proove two properties concerning the connections between Partial Least Squares (PLS) dimension reduction and between-group PCA, and between linear discriminant analysis and between ...
Boulesteix, Anne-Laure
core   +3 more sources

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich, Manali Zope, Peter M. Fantozzi, Cassie N. Kline, Iris Paltin, Matthew C. Hocking   +5 more
wiley   +1 more source

Prognostic differences between persistent HFrEF and HFrecEF following acute myocardial infarction

Frontiers in Cardiovascular Medicine
BackgroundAcute myocardial infarction (AMI) often leads to heart failure with reduced ejection fraction (HFrEF), with some patients showing recovery of left ventricular ejection fraction (HFrecEF) over time.
Jeong Yoon Jang, Jae Myoung Lee, Yujin Shin, Yong-Lee Kim, Gain Yu, Jae Seok Bae, Yun-Ho Cho, Choong Hwan Kwak, Min Gyu Kang, Kye-Hwan Kim, Jeong Rang Park, Jin-Yong Hwang, Young-Hoon Jeong, Jong-Hwa Ahn   +13 more
doaj   +1 more source