Results 61 to 70 of about 681,040 (233)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Persons with disabilities support services needs and utilization in Kenya: a study in preparation of a disability policy brief [PDF]

, 2017
Philosophiae Doctor - PhD (Physiotherapy)The interaction between impairment and environmental factors impose a certain degree of incapacity on individuals, often undermining their freedom to function.
Matheri, Joseph Mwangi
core   +1 more source

The status and predictors of self‐care among older adults with hypertension in China using the Chinese version of Self‐Care of Hypertension Inventory – A cross‐sectional study

Nursing Open, 2022
Aim To investigate the status and predictors of self‐care among older adults with hypertension in China by the Chinese version of Self‐Care of Hypertension Inventory. Design A cross‐sectional questionnaire survey.
Yu‐Jie Guo, Xiao‐Yun Hu, Hong‐Juan Ji, Qiao Zhao, Long‐Yuan Wang, Xiao‐Yan Zhou, Jue Tang, Lei Yang, Xiang‐Chao Sun   +8 more
doaj   +1 more source

Predictors of hematoma expansion predictors after intracerebral hemorrhage

Oncotarget, 2017
Despite years of effort, intracerebral hemorrhage (ICH) remains the most devastating form of stroke with more than 40% 30-day mortality worldwide. Hematoma expansion (HE), which occurs in one third of ICH patients, is strongly predictive of worse prognosis and potentially preventable if high-risk patients were identified in the early phase of ICH.
Chen, Sheng, Zhao, Binjie, Wang, Wei, Shi, Ligen, Reis, Cesar, Zhang, Jianmin   +5 more
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Factors associated with chronotype in individuals with bipolar disorder in remission

Indian Journal of Psychiatry
Background: Chronotype is trait-like construct reflecting long-term morningness–eveningness preferences. Higher eveningness scores are linked to sleep disturbances, night-eating, and addictive behaviors but remain understudied in subjects with bipolar ...
Ravneet Singh, Raman Deep, Vaibhav Patil, Rachna Bhargava, Ashwani Kumar Mishra   +4 more
doaj   +1 more source

The Predictors study: Development and baseline characteristics of the Predictors 3 cohort

Alzheimer's & Dementia, 2016
AbstractIntroductionThe Predictors study was designed to predict the length of time to major disease outcomes in Alzheimer's disease (AD) patients. Here, we describe the development of a new, Predictors 3, cohort.MethodsPatients with prevalent or incident AD and individuals at‐risk for developing AD were selected from the North Manhattan community and ...
Stern, Yaakov, Gu, Yian, Cosentino, Stephanie, Azar, Martina, Lawless, Siobhan, Tatarina, Oksana   +5 more
openaire   +4 more sources

Identifying potential predictors of traumatic reactions to psychotic episodes.

, 2006
OBJECTIVES: The experience of a psychotic episode can sometimes lead to post-traumatic stress disorder (PTSD) symptoms. The objective of the research was to identify candidate predictors of such negative reactions for future prospective study.
Anne Cooke, Freeman, Daniel, Chisholm, B., Freeman, D, Cooke, A., Daniel Freeman, Chisholm, B, Brock Chisholm, Cooke, A, Freeman, D.   +9 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Suture-Mediated Patent Fossa Ovalis Closure

JACC: Advances
Background: At short-term follow-up, percutaneous suture-mediated patent fossa ovalis (PFO) closure appears as a safe and effective alternative to device-based methods.
Achille Gaspardone, MD, MPhil, Gregory A. Sgueglia, MD, PhD, Antonella De Santis, MD, Fabiana Piccioni, MD, Emanuela D’Ascoli, MD, Tommasa Siragusa, RCIS, Maria Iamele, MD, Maria Benedetta Giannico, MD, Fabrizio D’Errico, MD, Carlo Gaspardone, MD   +9 more
doaj   +1 more source