Results 81 to 90 of about 985,541 (248)

Predictors of patient satisfaction

open access: yesSocial Science & Medicine, 2001
Correlates of patient satisfaction at varying points in time were assessed using a survey with 2-week and 3-month follow-up in a general medicine walk-in clinic, in USA. Five hundred adults presenting with a physical symptom, seen by one of 38 participating clinicians were surveyed and the following measurements were taken into account: patient symptom
Jackson, Jeffrey L   +2 more
openaire   +3 more sources

Hemorrhagic stroke and atherogenic markers – is there any relation?

open access: yesJournal of Family Medicine and Primary Care
Background: The triglyceride/high-density lipoprotein (TG/HDL) ratio emerges as a promising marker for cardiovascular risk. However, the relationship between overall serum lipid levels and hemorrhagic stroke (HS) remains uncertain.
Nejra Masic   +7 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Pattern and Predictors of Maternal Healthcare Services Utilization among Women of Reproductive Age in Lagos, Nigeria

open access: yesAnnals of Global Health
Background: The world still grapples with alarming maternal mortality rates, particularly in developing nations, including Nigeria. Annual global deaths exceed 500,000, predominantly in developing countries (99%) and sub‑Saharan Africa (over 50%), where ...
Esther Oluwakemi Oluwole   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Predictors of client satisfaction with family planning services in Ethiopia: a systematic review and meta-analysis

open access: yesFrontiers in Global Women's Health
BackgroundThe use of modern contraceptives by married Ethiopian women has increased over the past 15 years. Despite a few studies reporting different predictors of satisfaction with family planning services, there is a lack of nationwide data showing the
Yeshiwas Ayale Ferede   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Parietal alpha and theta power predict cognitive training gains in middle-aged adults

open access: yesFrontiers in Aging Neuroscience
Research on executive functions training shows inconsistent outcomes, with factors like age, baseline cognitive abilities, and personality traits implicated as predictive of training gains, while limited attention has been given to neurophysiological ...
Luka Juras   +2 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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