Results 81 to 90 of about 2,674,866 (251)
Concentration inequalities of the cross-validation estimate for stable predictors [PDF]
, 2010 In this article, we derive concentration inequalities for the cross-validation estimate of the generalization error for stable predictors in the context of risk assessment.
Cornec, Matthieu
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Stambaugh correlations, monkey econometricians and redundant predictors [PDF]
, 2011 We consider inference in a widely used predictive model in empirical finance. "Stambaugh Bias" arises when innovations to the predictor variable are correlated with those in the predictive regression. We show that high values of the "Stambaugh Correlation"
Robertson, D., Wright, Stephen
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
VirusesBackground/Objectives: Millions of individuals worldwide continue to experience symptoms following SARS-CoV-2 infection. This study aimed to assess the prevalence and phenotype of multi-system symptoms attributed to Long COVID—including fatigue, pain ...
Gili Joseph +13 more
doaj +1 more source
Predictors of discordance among Chilean families [PDF]
, 2012 Parent-youth agreement on parental behaviors can characterize effective parenting. Although discordance in families may be developmentally salient and harmful to youth outcomes, predictors of discordance have been understudied, and existing research in
Castillo, M. +5 more
core
Cluster-Aided Mobility Predictions
, 2016 Predicting the future location of users in wireless net- works has numerous applications, and can help service providers to improve the quality of service perceived by their clients. The location predictors proposed so far estimate the next location of a
Jeong, Jaeseong +2 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source