Results 101 to 110 of about 2,674,866 (251)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
An Embarrassment of Riches: Forecasting Using Large Panels [PDF]
The problem of having to select a small subset of predictors from a large number of useful variables can be circumvented nowadays in forecasting. One possibility is to efficiently and systematically evaluate all predictors and almost all possible models ...
Jana Eklund, Sune Karlsson
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Frontiers in ImmunologyPurposeThis study assessed the predictive value of dynamic laboratory parameter changes before and after intravenous immunoglobulin (IVIG) treatment for IVIG resistance in children with Kawasaki disease (KD).MethodsChildren with KD were stratified based ...
Zhiyuan Liu +14 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
CLINICAL AND X-RAY SPECIFICS OF SARCOIDOSIS DETECTED IN TUBERCULOSIS CONTROL SERVICES
Туберкулез и болезни лёгких, 2015 The current diffculties of differential diagnostics of pulmonary sarcoidosis have been analyzed in 58 patients. The duration of the diagnostic period has been described.
Zh. A. Laushkina +2 more
doaj
The heterogeneous life space trajectories and predictors in stroke patients: a cohort study
Frontiers in NeurologyObjectiveThis study aimed to identify heterogeneous trajectories of life space among stroke patients and explore the predictors for different classes of life space.MethodsThis prospective cohort study assessed 210 stroke patients’ life space at baseline ...
Bei Yang +6 more
doaj +1 more source
Exploring the Trust Gap: Dimensions and Predictors of Trust Among Labor and Management Representatives [PDF]
, 1992 Existing literature on interpersonal trust in work relationships has largely focused on trust as an independent variable. This study examined trust as a dependent variable by investigating its dimensions and predictors.
Currall, Steven C., Judge, Timothy A.
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
International Journal of MycobacteriologyBackground: Diagnostic delay among tuberculosis (TB) patients leads to late anti-TB treatment initiation, which is associated with poor prognosis and increased TB transmission.
Hazratullah Bariz +4 more
doaj +1 more source