Results 51 to 60 of about 936,691 (247)

The prevalence of erectile dysfunction and its associated factors among diabetic patients in the Southwestern Region of Saudi Arabia analytical cross-sectional study [PDF]

Journal of Men's Health
Background: Erectile dysfunction (ED) is a common condition among diabetic patients, significantly affecting their quality of life. This study examines the prevalence of ED and the factors contributing to its occurrence among diabetic patients in the ...
Safar Saad Battar, Faisal Saeed Al-Qahtani, Mohammed Mansour M. Alqahtani, Rayyan Mohammed A. Alassiri, Abdulrhman Saeid Z. Alshahrani, Mohammed Ahmed M. Alhanash, Nawaf Faris A. Alnahdi, Saad Ali S. Alasiri, Abdulaziz Saud S. Alotaibi, Ali Mohammed AlAmri   +9 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Nanoscopic Cancer Biomarkers Characterization of Extracellular Vesicles in Liquid Biopsy

The Journal of Liquid Biopsy, 2023
M. Triki, M. Pagliuca, C. Schietroma, Q. Lubart, C. Butler, B. Verret, A. Italiano, F. André   +7 more
doaj   +1 more source

Time to antenatal care booking and its predictors among pregnant women in East Africa: a Weibull gamma shared frailty model using a recent demographic and health survey

Frontiers in Global Women's Health
BackgroundAntenatal care (ANC) is an important component of maternal and child healthcare. The World Health Organization (WHO) recommends that pregnant women book their ANC contact at or before 12 weeks of gestational age.
Abel Endawkie, Shimels Derso Kebede, Kaleab Mesfin Abera, Eyob Tilahun Abeje, Ermias Bekele Enyew, Chala Daba, Lakew Asmare, Fekade Demeke Bayou, Mastewal Arefaynie, Anissa Mohammed, Abiyu Abadi Tareke, Awoke Keleb, Natnael Kebede, Yawkal Tsega   +13 more
doaj   +1 more source

Echocardiographic predictors of atrial fibrillation recurrence after catheter ablation: A literature review

Cardiology Journal, 2020
BACKGROUND: Catheter ablation (CA) is a well-known treatment option for patients with symptomatic drug-resistant atrial fibrillation (AF). Multiple factors have been identified to determine AF recurrence after CA, however their predictive value is rather
Aleksandra Liżewska-Springer, Alicja Dąbrowska-Kugacka, Ewa Lewicka, Łukasz Drelich, Tomasz Królak, Grzegorz Raczak   +5 more
doaj   +1 more source

Predictors of Atherosclerosis

Journal of Atherosclerosis and Thrombosis, 2004
It is herein discussed what should be measured as predictors of atherosclerosis, to increase the predictive power of coronary risk evaluation in clinical practice. Plasma apolipoprotein (apo)B and apoAI have been reported to be stronger predictors of coronary artery disease (CAD) than plasma low-density lipoprotein (LDL)-cholesterol (C) and high ...
openaire   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Applying a clinical staging model in patients affected by schizophrenia spectrum disorder

Frontiers in Psychiatry
BackgroundClinical staging, already widespread in medicine, represents a new frontier in psychiatry. Our goal was to convert the existing theoretical staging model for schizophrenia into a feasible tool to have a timely assessment of patients’ health ...
Renato de Filippis, Elvira Anna Carbone, Marianna Rania, Matteo Aloi, Matteo Aloi, Cristina Segura-Garcia, Pasquale De Fazio   +6 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source