Effect of Dupilumab on Airway Inflammation in Patients With Persistent Asthma
EXPEDITION (NCT02573233) assessed the effects of dupilumab on airway inflammation in patients with persistent asthma using bronchoscopy and gene expression analysis. Dupilumab showed no appreciable effect on inflammatory cell types in biopsies or BALF samples.
Michael E. Wechsler +22 more
wiley +1 more source
Recurrent Immune Checkpoint Inhibitor Hepatitis With Pembrolizumab Cessation: A Stubborn Case of Delayed-Onset, Steroid-Refractory Hepatotoxicity. [PDF]
Ladetto A, Gildea DT, Shenoy A.
europepmc +1 more source
Acute hypothalamic–pituitary–ovarian axis suppression is common in anti‐NMDAR encephalitis, yet ovarian function and fertility recover favorably even in teratoma‐associated cases, supporting reassuring long‐term reproductive prognoses. Abstract Introduction Anti‐N‐methyl‐D‐aspartate receptor (anti‐NMDAR) encephalitis predominantly affects women of ...
Jia Wang +4 more
wiley +1 more source
Corticosteroid use, bone density screening, and the influence of insurance in patients with inflammatory bowel disease: a retrospective analysis. [PDF]
Reddy A +6 more
europepmc +1 more source
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen +3 more
wiley +1 more source
The Effect of Prednisone and Levothyroxine Sodium on Miscarriage Risk and Thyroid Function in Patients with High TPOAb Concentrations: A Retrospective Cohort Study. [PDF]
Qiu YM, Qin ZW, Lin J, Yang Y.
europepmc +1 more source
The role of pain in Graves' orbitopathy: Associations with clinical activity and quality of life
Abstract Purpose Pain is included in the clinical activity score (CAS) as an indicator of inflammatory activity in Graves' orbitopathy (GO), yet its clinical relevance has not been systematically evaluated. We therefore investigated the relationship between pain, other inflammatory signs and quality of life (QoL), and assessed the effect of intravenous
Gijsbert J. Hötte +7 more
wiley +1 more source
Uveitis in pediatric idiopathic orbital inflammatory syndrome. [PDF]
Choi A +7 more
europepmc +1 more source
Objective To report 45 cases of melioidosis in dogs and cats from northern Australia and analyse trends in epidemiology, clinical presentation, pathogenesis and response to treatment over a 27‐year period. Design Retrospective and prospective analysis of clinical records.
K Lee +6 more
wiley +1 more source
Aplastic Anemia Proceeding to Thymoma: A Rare Co-Occurrence-A Case Report and Review Article. [PDF]
Ghazizadeh M, Ghazizadeh M, Moini M.
europepmc +1 more source

