Results 41 to 50 of about 117,571 (283)

Prolactin and risk of preeclampsia: A single institution, cross-sectional study

Asian Pacific Journal of Reproduction, 2019
Objective: To illustrate the association between prolactin serum level and severity of preeclampsia. Methods: In this cross-sectional study, 31 pregnant women with preeclampsia were enrolled as Group I and 20 healthy pregnant women as Group II.
Thabat J Al-Maiahy, Ali I Al-Gareeb, Hayder M Al-kuraishy   +2 more
doaj   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

The common variant rs11646213 is associated with preeclampsia in Han Chinese women. [PDF]

PLoS ONE, 2013
BACKGROUND: Preeclampsia, characterized by hypertension and proteinuria, is a multifactorial disease caused by complex interactions between environmental and genetic factors.
Ji-peng Wan, Han Zhao, Tao Li, Chang-zhong Li, Xie-tong Wang, Zi-Jiang Chen   +5 more
doaj   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Perinatal depression and anxiety in Ghana: a qualitative study of women's perspectives on AI-driven interventions

BMC Pregnancy and Childbirth
Background The perinatal period is critical for maternal and child health, yet many women experience perinatal mental illnesses, particularly perinatal depression and anxiety.
Ayomide Oluwaseyi Oladosu, Clinton Sekyere Frempong, Uchechi Shirley Anaduaka, Samantha Katsande, Success Amador-Awuku   +4 more
doaj   +1 more source

An angiogenic marker for early prediction of preeclampsia

Asian Journal of Medical Sciences, 2022
Background: Preeclampsia is a pregnancy-specific disease associated with a high incidence of maternal and fetal morbidity and mortality with classical features of hypertension, proteinuria, and edema. Aims and Objectives: The aims of the study were to
Archana A , Sumitha A , Sathiyapriya V , Ursula Sampson   +3 more
doaj   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Co-creation of a toolkit to assist risk communication and clinical decision-making in severe preeclampsia: SPOT-Impact study design

Global Health Action
Globally, the incidence of hypertensive disorders of pregnancy, especially preeclampsia, remains high, particularly in low- and middle-income countries.
Hannah Brown Amoakoh, Bregje C. De Kok, Linda Lucy Yevoo, Klaartje M. Olde Loohuis, Emmanuel K. Srofenyoh, Daniel K. Arhinful, Koiwah Koi-Larbi, Kwame Adu-Bonsaffoh, Mary Amoakoh-Coleman, Joyce L. Browne   +9 more
doaj   +1 more source

RELATIONSHIP BETWEEN OBESITY, TWIN-PREGNANCY AND PREVIOUS HISTORY OF PREECLAMPSIA WITH PREECLAMPSIA

Indonesian Midwifery and Health Sciences Journal, 2021
Background: Preeclampsia can threaten the health of the mother and fetus during pregnancy and childbirth, besides that it also increases the risk of long-term complications and has the potential to cause death.
Riani Widia Parantika, Gatut Hardianto, Muhammad Miftahussurur, Wahyul Anis   +3 more
doaj   +1 more source