Results 61 to 70 of about 136,617 (305)

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source

Co-creation of a toolkit to assist risk communication and clinical decision-making in severe preeclampsia: SPOT-Impact study design

Global Health Action
Globally, the incidence of hypertensive disorders of pregnancy, especially preeclampsia, remains high, particularly in low- and middle-income countries.
Hannah Brown Amoakoh, Bregje C. De Kok, Linda Lucy Yevoo, Klaartje M. Olde Loohuis, Emmanuel K. Srofenyoh, Daniel K. Arhinful, Koiwah Koi-Larbi, Kwame Adu-Bonsaffoh, Mary Amoakoh-Coleman, Joyce L. Browne   +9 more
doaj   +1 more source

Placental Growth Factor Levels in Preeclampsia Compared to Normal Pregnancy

Indonesian Journal of Obstetrics and Gynecology, 2015
Objective: To identify and analyze the differences in the levels of PlGF in preeclampsia and normal pregnancy. Method: This was a cross-sectional observational qualitative study of PlGF in preeclampsia and normal pregnancy. The number of samples in
Dumaria Situmorang, Hermie MM Tendean, John J Wantania   +2 more
doaj   +1 more source

RELATIONSHIP BETWEEN OBESITY, TWIN-PREGNANCY AND PREVIOUS HISTORY OF PREECLAMPSIA WITH PREECLAMPSIA

Indonesian Midwifery and Health Sciences Journal, 2021
Background: Preeclampsia can threaten the health of the mother and fetus during pregnancy and childbirth, besides that it also increases the risk of long-term complications and has the potential to cause death.
Riani Widia Parantika, Gatut Hardianto, Muhammad Miftahussurur, Wahyul Anis   +3 more
doaj   +1 more source

Preeclampsia

, 2019
Preeclampsia is a common pregnancy condition that is poorly understood and lacks effective treatments. This thesis explores and identifies several new aspects relating to preeclampsia, ranging from pathophysiology, to clinical correlations, novel ...
SEBASTIAN RUPERT HOBSON (6517109)
core   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source

Is postpartum preeclampsia a continuation of intrapartum preeclampsia? Maternal risk factors in intrapartum vs. postpartum preeclampsia: a retrospective cohort study

BMC Pregnancy and Childbirth
Objective To compare maternal characteristics and risk factors associated with intrapartum and postpartum preeclampsia in relation to pregnancies without preeclampsia.
Hila Shalev-Ram, Talish Razi, Dorit Ravid, Hezzy Shmueli, Ronen Arbel, Tal Biron-Shental   +5 more
doaj   +1 more source

Evaluation of current and new biomarkers in severe preeclampsia: a microarray approach reveals the VSIG4 gene as a potential blood biomarker.

PLoS ONE, 2013
Preeclampsia is a placental disease characterized by hypertension and proteinuria in pregnant women, and it is associated with a high maternal and neonatal morbidity.
Julien Textoris, Delphine Ivorra, Amira Ben Amara, Florence Sabatier, Jean-Pierre Ménard, Hélène Heckenroth, Florence Bretelle, Jean-Louis Mege   +7 more
doaj   +1 more source

Implantation‐On‐Chip: An AI‐Based Platform for Monitoring the Embryo Trophoblast–Endometrial Stroma Cross Talk With Xenobiotics Interference

Advanced Intelligent Systems, EarlyView.
We present a novel AI‐integrated implantation‐on‐chip platform that enables mimicking and monitoring the maternal–fetal interactions at the early phases of human embryo implantation with high spatiotemporal resolution. The complexity of the trophoblast invasion process was addressed by conducting the analysis at global (rate of invasion) and local ...
Joanna Filippi, Valentina Lacconi, Arianna Mencattini, Micol Massimiani, Dolores Lobresca, Gaia Posanzini, Alessia Riccardi, Paola Casti, Michele D’Orazio, Gianni Antonelli, Giorgia Curci, Luisa Campagnolo, Eugenio Martinelli   +12 more
wiley   +1 more source

Prolactin and risk of preeclampsia: A single institution, cross-sectional study

Asian Pacific Journal of Reproduction, 2019
Objective: To illustrate the association between prolactin serum level and severity of preeclampsia. Methods: In this cross-sectional study, 31 pregnant women with preeclampsia were enrolled as Group I and 20 healthy pregnant women as Group II.
Thabat J Al-Maiahy, Ali I Al-Gareeb, Hayder M Al-kuraishy   +2 more
doaj   +1 more source