Results 91 to 100 of about 550,362 (263)

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

The "more is less" phenomenon in Contingent and Inferred valuation [PDF]

open access: yes
2011) using the Contingent valuation (CV) as well as the Inferred valuation (IV) method (Lusk and Norwood 2009b). We find that when moving in the context of a familiar market for consumers (i.e., the food market) we only observe weak effects of ...
Drichoutis, Andreas C.   +2 more
core  

Continuous process tracing and the Iowa Gambling Task: Extending response dynamics to multialternative choice [PDF]

open access: yesJudgment and Decision Making, 2011
The history of judgment and decision making is defined by a trend toward increasingly nuanced explanations of the decision making process. Recently, process models have become incredibly sophisticated, yet the tools available to directly test these ...
Gregory J. Koop, Joseph G. Johnson
doaj  

Sequential sampling model for multiattribute choice alternatives with random attention time and processing order

open access: yesFrontiers in Human Neuroscience, 2014
A sequential sampling model for multiattribute binary choice options, called Multiattribute attention switching (MAAS) model, assumes a separate sampling process for each attribute.
Adele eDiederich, Peter eOswald
doaj   +1 more source

Postscript: Contrasting predictions for preference reversal.

open access: yesPsychological Review, 2010
In this post scrit, the authors discuss an article by Hotaling, Busemeyer, and Li (see record 2010-22285-008) which provided a valuable reply to the challenges the current authors raised for the decision field theory (DFT) account of preference reversal in multiattribute choice.
Marius Usher   +2 more
openaire   +3 more sources

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Observed and Normative Discount Functions in Addiction and other Diseases

open access: yesFrontiers in Pharmacology, 2017
The aim of this paper is to find a suitable discount function able to describe the progression of a certain addiction or disease under treatment as a discounting process.
Salvador Cruz Rambaud   +2 more
doaj   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

open access: yesFEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao   +23 more
wiley   +1 more source

Preference Reversals in Discrete Choice Experiments. Inattention or Preference Uncertainty? Some Evidence Using Eyetracking [PDF]

open access: yes, 2019
We investigate the relationship between visual attention and attendence with the rate of "preference reversals" in a discrete choice experiment (DCE) that employed eyetracking.
Balcombe, Kelvin   +3 more
core   +1 more source

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