Results 91 to 100 of about 2,674,560 (334)

One size does (obviously not) fit all: Using product attributes for wine market segmentation [PDF]

open access: yes, 2017
The intense competition affecting the wine industry in recent decades has forced wineries and retailers to reshape their marketing strategies on the basis of consumer preferences.
Chrysochou, Polymeros   +4 more
core   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Low public awareness opens up new opportunities for highlighting milk as an iodine dietary source

open access: yesJournal of Dairy Science
: This international survey provides insights into public awareness of the importance of iodine as an essential trace mineral in human health along with knowledge of iodine dietary sources.
Giovanni Niero   +21 more
doaj   +1 more source

A note on selecting maximals in finite spaces [PDF]

open access: yes, 2012
Given a choice problem, the maximization rule may select many alternatives. In such cases, it is common practice to interpret that the final choice will end up being made by some random procedure, assigning to any maximal alternative the same ...
García-Bermejo, Juan Carlos
core   +1 more source

Environmental protection and the generalized system of preferences : a legal and appropriate linkage? [PDF]

open access: yes, 2008
This article will question the legality of measures of environmental ‘conditionality’ in the Generalized System of Preferences [GSP] of the European Community [EC].
Switzer, Stephanie
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Sustainable Management of an Urban Green Space in a Papua New Guinean City: Accessibility, Use and Preferences

open access: yesUrban Science
Urban green spaces provide recreation opportunities that contribute to physical wellbeing, health, and social wellbeing. However, managing green spaces to promote access and use for recreation and at the same time meet the preferences of visitors is ...
Eugene Ejike Ezebilo
doaj   +1 more source

Psychological type profile of religiously committed male and female Canadian Baptist youth: a study among participants at tidal impact [PDF]

open access: yes, 2009
A sample of 479 female and 274 male religiously committed Canadian youth over the age of 11 years completed the Adolescent Form of the Francis Psychological Type Scales (FPTSA) within the context of a weeklong mission and service event sponsored by the ...
Fawcett, Bruce G.   +2 more
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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