Results 91 to 100 of about 2,479,013 (284)

GUIDELINE DEVELOPMENT FOR PROJECT DECISION MAKING BASED ON METHODOLOGY OF QUALITY FUNCTION STRUCTURING

open access: yesВісник Національного технічного університету «ХПÌ». Серія: Стратегічне управління, управління портфелями, програмами та проектами, 2015
Analysis for the existing experience of using quality function deployment methodology was performed in the article. The features of the methodology implementation in project activities are considered and the deployment tasks in its separate stages are ...
Василь Дмитрович ШПИЛЬОВИЙ   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Low public awareness opens up new opportunities for highlighting milk as an iodine dietary source

open access: yesJournal of Dairy Science
: This international survey provides insights into public awareness of the importance of iodine as an essential trace mineral in human health along with knowledge of iodine dietary sources.
Giovanni Niero   +21 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Sustainable Management of an Urban Green Space in a Papua New Guinean City: Accessibility, Use and Preferences

open access: yesUrban Science
Urban green spaces provide recreation opportunities that contribute to physical wellbeing, health, and social wellbeing. However, managing green spaces to promote access and use for recreation and at the same time meet the preferences of visitors is ...
Eugene Ejike Ezebilo
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Mechanism Design for Data Science

open access: yes, 2014
Good economic mechanisms depend on the preferences of participants in the mechanism. For example, the revenue-optimal auction for selling an item is parameterized by a reserve price, and the appropriate reserve price depends on how much the bidders are ...
Chawla, Shuchi   +2 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Climate services bundles preferences of smallholder farmers in West Africa: a stated choice modelling

open access: yesFrontiers in Climate
This study investigates the preferences of rainfed farmers in West Africa for bundled agroclimate services, addressing challenges posed by climate variability and limited purchasing power.
Adama Ouedraogo   +8 more
doaj   +1 more source

Local Preferences and Place of Death in Regions within England 2010 [PDF]

open access: yes, 2011
This report shows public preferences for place of death in the nine English Government Office Regions (GORs), obtained from a population-based telephone survey in 2010.
Barbara Gomes   +2 more
core  

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