Results 91 to 100 of about 506,177 (268)
Open AgricultureHumans have been consuming milk obtained from domesticated animals since ancient times. Milk is a very complete food with important nutrients that can support life. However, the patterns of consumption of milk have been shifting.
Guiné Raquel P. F. +6 more
doaj +1 more source
PharmacyThe process of evaluation and selection of drugs in Spain is currently changing, with hospital pharmacists (HPs) having a growing relevance. This cross-sectional observational study aimed to assess HPs’ preferences for different hypothetical intravitreal
José Luis Poveda +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Sequential effects in preference decision: Prior preference assimilates current preference
PLOS ONE, 2017 An important factor affecting preference formation is the context in which that preference decision takes place. The current research examined whether one's preference formed for a previously presented stimulus influences the processing of a subsequent preference decision, henceforth referred to as the preference sequence effect.
Seah Chang, Chai-Youn Kim, Yang Seok Cho
openaire +4 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
PENGARUH NILAI DAN GAYA HIDUP TERHADAP PREFERENSI DAN PERILAKU PEMBELIAN BUAH-BUAHAN IMPOR
Jurnal Ilmu Keluarga dan Konsumen, 2013 This study was intended to determine the influence of values and lifestyle on the preferences and purchasing behavior of imported fruits. This study applied cross sectional design and involved 60 housewives which were randomly selected.
Astari Sukmaningtyas, Hartoyo Hartoyo
doaj +1 more source
On the Role of Preference Variance in Preference Optimization
CoRRDirect Preference Optimization (DPO) has emerged as an important approach for learning from human preferences in aligning large language models (LLMs). However, collecting human preference data is costly and inefficient, motivating methods to reduce the required annotations.
Jiacheng Guo +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source