Results 111 to 120 of about 409,500 (359)
Functions of delay-period activity in the prefrontal cortex and mnemonic scotomas revisited
Frontiers in Systems Neuroscience, 2015 Working memory is one of key concepts to understand functions of the prefrontal cortex. Delay-period activity is an important neural correlate to understand the role of working memory in prefrontal functions.
Shintaro eFunahashi
doaj +1 more source
The role of prefrontal cortex in psychopathy [PDF]
Reviews in the Neurosciences, 2012 Psychopathy is a personality disorder characterized by remorseless and impulsive antisocial behavior. Given the significant societal costs of the recidivistic criminal acti\xadvity associated with the disorder, there is a pressing need for more effective treatment strategies and, hence, a better understanding of the psychobiological mechanisms ...
openaire +3 more sources
Human Brain Cell‐Type‐Specific Aging Clocks Based on Single‐Nuclei Transcriptomics
Advanced Science, EarlyView.Muralidharan and colleagues develop cell‐type‐specific transcriptomic aging clocks using single‐nucleus RNA sequencing of human post mortem prefrontal cortex samples. These clocks accurately predict age and identify distinct aging trajectories in specific brain cell types.
Chandramouli Muralidharan +12 more
wiley +1 more source
Frontiers in Neuroscience, 2013 The False Tagging Theory (FTT) is a neuroanatomical model of belief and doubt processes that proposes a single, unique function for the prefrontal cortex.
Erik William Asp +5 more
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Prefrontal Activity Links Nonoverlapping Events in Memory [PDF]
, 2013 The medial prefrontal cortex (mPFC) plays an important role in memory. By maintaining a working memory buffer, neurons in prelimbic (PL) mPFC may selectively contribute to learning associations between stimuli that are separated in time, as in trace fear
Diba, Kamran +3 more
core +2 more sources
Dynamic Neural Deactivation Bridges Direct and Competitive Inhibition Processes
Advanced Science, EarlyView.Dynamic neural deactivation bridges traditionally distinct inhibitory mechanisms—direct inhibition and competition‐induced inhibition—revealing a common neural signature across modalities. Multimodal neuroimaging and behavioral experiments demonstrate a temporal dynamic characterized by progressive frontoparietal activation decay and enhanced sensory ...
Zhenhong He +6 more
wiley +1 more source
Space representation in the prefrontal cortex [PDF]
Progress in Neurobiology, 2013 The representation of space and its function in the prefrontal cortex have been examined using a variety of behavioral tasks. Among them, since the delayed-response task requires the temporary maintenance of spatial information, this task has been used to examine the mechanisms of spatial representation.
openaire +3 more sources
Integration of Genetic and Imaging Data for Alzheimer's Disease Diagnosis and Interpretation
Advanced Science, EarlyView.AlzCLIP is a novel contrastive learning framework that integrates single nucleotide polymorphism (SNP) profiles and MRI‐derived imaging features into a unified representation space to improve Alzheimer's disease (AD) diagnosis and interpretation. By achieving superior diagnostic accuracy and revealing key genetic and structural contributors to AD risk,
Yanfei Wang +7 more
wiley +1 more source
Frontiers in Neural Circuits, 2008 The prefrontal cortex has been extensively implicated in autism to explain deficits in executive and other higher-order functions related to cognition, language, sociability and emotion.
Tania Rinaldi +3 more
doaj +1 more source
Capacity and tendency: A neuroscientific framework for the study of emotion regulation. [PDF]
, 2019 It is widely accepted that the ability to effectively regulate one's emotions is a cornerstone of physical and mental health. As such, it should come as no surprise that the number of neuroimaging studies focused on emotion regulation and associated ...
Guassi Moreira, João F +1 more
core +2 more sources