Results 161 to 170 of about 386,459 (384)

Pharmacokinetic analysis on compatibility of Atractylodes macrocephala and Paeoniae radix herb pair ameliorates functional constipation model rats using microdialysis with ultra‐performance liquid chromatography

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The active ingredient of the drug determines the effect of the drug, and the compatibility affects the content of the active ingredient of the drug, which in turn affects the exertion of the efficacy. This study partly clarifies the rationality and compatibility of AM‐PR in the treatment of FC.
Xiaoting Wang   +4 more
wiley   +1 more source

Effects of neonatal thermal lesioning of the mesocortical dopaminergic projection on the development of the rat prefrontal cortex [PDF]

open access: green, 1987
Andries Kalsbeek   +5 more
openalex   +1 more source

Larger mid-dorsolateral prefrontal gray matter volume in young binge drinkers revealed by voxel-based morphometry.

open access: yesPLoS ONE, 2014
Binge drinking or heavy episodic drinking is a high prevalent pattern of alcohol consumption among young people in several countries. Despite increasing evidence that binge drinking is associated with impairments in executive aspects of working memory (i.
Sonia Doallo   +5 more
doaj   +1 more source

Alterations in gut microbiota and metabolites contribute to postoperative sleep disturbances

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this study, we classified postoperative patients into poor sleepers (PS) and good sleepers (GS) based on the bispectral index (BIS), and transplanted their fecal microbiota to pseudo‐germ‐free rats to analyze the sleep changes in rats and the potential mechanism.
Hui Zhong   +7 more
wiley   +1 more source

Punica granatum peel supplementation attenuates cognitive deficits and brain injury in rat by targeting the Nrf2‐HO‐1 pathway

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 168-180, January 2023., 2023
The hydro‐ethanolic extract of P. granatum peel was standardized. ;The extract increased superoxide dismutase activity and thiol content, while reduced function of AchE and peroxidation of lipid in the scopolamine‐injured rat’s brain. ;P. granatum may attenuate scopolamine injury through targeting nuclear factor‐E2‐related factor 2 pathway ; Abstract ...
Mahsan Akbarian   +5 more
wiley   +1 more source

Anatomical Connections of Primate Mediodorsal and Motor Thalamic Nuclei with the Cortex [PDF]

open access: yesarXiv
Non-sensory thalamic nuclei interact with the cortex through thalamocortical and cortico-basal ganglia-thalamocortical loops. Reciprocal connections between the mediodorsal thalamus (MD) and the prefrontal cortex are particularly important in cognition, while the reciprocal connections of the ventromedial (VM), ventral anterior (VA), and ventrolateral (
arxiv  

Effects of pregnancy on neuron electrophysiology in prefrontal cortex, hippocampus, and basolateral amygdala of mouse brain

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The electrophysiological change in neurons might contribute to the cognitive and emotional changes during pregnancy. Abstract Background Pregnancy affects learning and memory in women. Thus, to investigate the effects of pregnancy, the authors examined the brain electrophysiology of pregnant mice.
Xuefan Bin, Huijuan Luo
wiley   +1 more source

Circadian modulation of microglial physiological processes and immune responses

open access: yesGlia, Volume 71, Issue 2, Page 155-167, February 2023., 2023
Main Points Microglia are rhythmic cells with an oscillatory expression in clock genes, cytokines, and other microglial markers. Microglial circadian rhythms determine their physiological function and immune responses. Abstract Microglia is considered the central nervous system (CNS) resident macrophages that establish an innate immune response against
Mara A. Guzmán‐Ruiz   +11 more
wiley   +1 more source

Krüppel‐like factor 4 transcription factor in blood–brain barrier endothelial cells: A potential role in Alzheimer's disease

open access: yesAnimal Models and Experimental Medicine, EarlyView.
KLF4 (Krüppel‐like factor 4) plays a protective role in blood–brain barrier (BBB). KLF4 plays an ambiguous role in the central nervous system. KLF4 in the BBB endothelial cells could be a potential target for Alzheimer's disease. Abstract Alzheimer's disease is the most prevalent chronic neurodegenerative disorder worldwide, with no sufficient cure ...
Ziying Wei   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy