Results 171 to 180 of about 386,459 (384)

Loss of oligodendrocyte ErbB receptor signaling leads to hypomyelination, reduced density of parvalbumin‐expressing interneurons, and inhibitory function in the auditory cortex

open access: yesGlia, Volume 71, Issue 2, Page 187-204, February 2023., 2023
Main Point Loss of oligodendrocyte ErbB receptor signaling leads to A1 hypomyelination, reduced PV expression and density of PV+ neurons and synapses, hypoconnectivity of inhibitory circuits and shift of the E/I balance towards excitation. Abstract For a long time, myelin was thought to be restricted to excitatory neurons, and studies on dysmyelination
Beatriz C. Borges   +4 more
wiley   +1 more source

A Pilot Study on the Comparison of Prefrontal Cortex Activities of Robotic Therapies on Elderly with Mild Cognitive Impairment [PDF]

open access: yesarXiv
Demographic shifts have led to an increase in mild cognitive impairment (MCI), and this study investigates the effects of cognitive training (CT) and reminiscence therapy (RT) conducted by humans or socially assistive robots (SARs) on prefrontal cortex activation in elderly individuals with MCI, aiming to determine the most effective therapy-modality ...
arxiv  

Functional magnetic resonance imaging of human prefrontal cortex activation during a spatial working memory task. [PDF]

open access: green, 1994
Gregory McCarthy   +7 more
openalex   +1 more source

Frequency and Early Predictors of Cognitive Deterioration in Amyotrophic Lateral Sclerosis: A Longitudinal Population‐Based Study

open access: yesAnnals of Neurology, EarlyView.
Objective The objective is to evaluate cognitive and behavioral progression and identify early predictors of these changes in a cohort of amyotrophic lateral sclerosis (ALS) patients. Methods A total of 161 ALS patients were tested at diagnosis (T0), and 107 were re‐tested after 1 year (T1) using cognitive/behavioral tests. All patients underwent whole‐
Barbara Iazzolino   +13 more
wiley   +1 more source

A subset of OPCs do not express Olig2 during development which can be increased in the adult by brain injuries and complex motor learning

open access: yesGlia, Volume 71, Issue 2, Page 415-430, February 2023., 2023
Main Points A subset of OPCs do not express Olig2, of which population peaks in the juvenile brain while wanes with age. Plastic changes of the brain by acute injuries or complex motor learning stop the expression of Olig2 in OPCs. Abstract Oligodendrocyte precursor cells (OPCs) are uniformly distributed in the mammalian brain; however, their function ...
Li‐Pao Fang   +7 more
wiley   +1 more source

ORGaNICs: A Theory of Working Memory in Brains and Machines [PDF]

open access: yesarXiv, 2018
Working memory is a cognitive process that is responsible for temporarily holding and manipulating information. Most of the empirical neuroscience research on working memory has focused on measuring sustained activity in prefrontal cortex (PFC) and/or parietal cortex during simple delayed-response tasks, and most of the models of working memory have ...
arxiv  

Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Signaling in The Prefrontal Cortex Modulates Cued Fear Learning, But Not Spatial Working Memory, in Female Rats [PDF]

open access: yes, 2018
A genetic polymorphism within the gene encoding the pituitary adenylate cyclase- activating polypeptide (PACAP) receptor type I (PAC1R) has recently been associated with hyper-reactivity to threat-related cues in women, but not men, with post-traumatic ...
Gilmartin, Marieke R.   +6 more
core   +1 more source

Prefrontal cortical thickness in motor neuron disease

open access: yesNeuroImage: Clinical, 2018
Objective: To examine whether the distribution of prefrontal cortical thickness in patients with motor neuron disease is normal or bimodal and how it compares to the normal population.
Judith Machts   +9 more
doaj  

Signs of Cortical Inflammation in Migraine Measured with Quantitative Magnetic Resonance Imaging: A Registry for Migraine (REFORM) Study

open access: yesAnnals of Neurology, EarlyView.
Objective The involvement of cortical inflammation in migraine, particularly migraine with aura, has been a subject of considerable interest, but has proved challenging to demonstrate. We aimed to detect and characterize signs of cortical inflammation in adults with migraine using a novel, multimodal magnetic resonance imaging (MRI) technique.
Rune H. Christensen   +8 more
wiley   +1 more source

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