Results 111 to 120 of about 598 (175)

Structure of 21-fluoro-4,9(11)-pregnadiene-3,20-dion-17α-yl acetate, C23H29O4F

Journal of Crystallographic and Spectroscopic Research, 1990
The crystal and molecular structure of 21-fluoro-4,9(ll)-pregnadiene-3,20-dion-17a-yl acetate has been determined by X-ray diffraction methods;P212121,a=15.827(4),b=16.912(4),c=7.513(2) A,Z=4;R=0.062, (R w =0.065) for 2028 unique observed reflections.
Z. Gałdecki, Paweł Grochulski, Z. Wawrzak, William L. Duax, P. Strong   +4 more
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In vivo and in vitro effect of novel 4,16-pregnadiene-6,20-dione derivatives, as 5α-reductase inhibitors

The Journal of Steroid Biochemistry and Molecular Biology, 2008
In this study, we report the synthesis and biological evaluation of several new 3-substituted pregna-4,16-diene-6,20-dione derivatives (11a-11d). These compounds were prepared from the commercially available 16-dehydropregnenolone acetate. The biological effect of these steroids was demonstrated in in vivo and in vitro experiments.
Eugene Bratoeff, Marisa Cabeza, Victor Pérez-Ornelas, Sergio Recillas‐Morales, Ivonne Heuze   +4 more
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Ethyl 3β-Acetoxy-5,17(20)-pregnadiene-21-thiolate

Journal of the American Chemical Society, 1951
Roger W. Jeanloz
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▵^4,7-PREGNADIENE-3,20-DIONE, A CORRECTION

The Journal of Organic Chemistry, 1952
Carl Djerassi, J. Romo, G. Rosenkranz
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Steroid derivatives. XXXIII. The formation and structure of 16-methyl-Δ14,16- pregnadiene derivatives

Collection of Czechoslovak Chemical Communications, 1964
R. Míčková, K. Syhora
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Hydroxy-17β méthoxy-11β méthyl-18 nor-19 pregnadiene-4,9 yne-20 one-3

Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry, 1981
J. Delettré, G. Lepicard, E. Surcouf, J.-P. Mornon   +3 more
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Structure of 6-methyl-3,20-dioxo-4,6-pregnadien-17?-yl acetate, C24H32O4

Journal of Crystallographic and Spectroscopic Research, 1992
The X-ray structure of 6-methyl-3,20-dioxo-4,6-pregnadien-17α-yl acetate is reported. The crystals are monoclinic, space groupP21,Z=4,a=28.955(7),b=6.597(2),c=11.064(3) A,/gb=90.80(2) °. The two crystallographically independent molecules have very similar overall geometries.
Zdzislaw Wawrzak, Pawel Grochulski, Zdzislaw Galdecki, Jane F. Griffin, Phyllis D. Strong, William L. Duax   +5 more
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Efficient Synthesis of Steroidal Intermediates with a C17 Side Chain from Phytosterols by Genetically Modified Mycolicibacterium neoaurum NRRL B‐3805 Strain

ChemistryOpen
22‐Hydroxy‐23,24‐bisnorchol‐4‐ene‐3‐one (4‐HBC) and 3‐oxo‐4,17‐pregnadiene‐20‐carboxylic acid methyl ester (PDCE) are useful precursors for the synthesis of steroidal active pharmaceutical ingredients.
Xuemei Li, Liangyan Zhu, Qiong Wu, Rui Zhang, Yiyin Liu, Na Liu, Jinhui Feng, Qiaqing Wu, Dunming Zhu   +8 more
semanticscholar   +1 more source

ChemInform Abstract: SYNTH. VON 17‐ACYLOXY‐3,5‐PREGNADIEN‐20‐ON‐DERIVATEN

Chemischer Informationsdienst. Organische Chemie, 1971
AbstractDurch selektive Reduktion mit Natriumborhydrid in Aceton in Gegenwart von Phosphormolybdänsäure werden die 3‐Hydroxy‐Derivate (II) und (V) erhalten, die durch Dehydratisierung die Pregnadien‐20‐on‐Derivate (III), (IV) und (Vii) liefern.
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Synthesis and Evaluation of Some Novel Pregnane Derivatives as Anti-Hyperlipidemic and Anti-Oxidant Agents

Letters in Organic Chemistry, 2018
In the present paper, synthesis of few novel pregnane derivatives and their evaluation as potential anti-hyperlipidemic and anti-oxidant agents has been reported. The synthesis of 3β-hydroxy- 16α-methoxy pregn-5-en-20-one (4) was achieved by reaction of
A. Sethi, Akriti Bhatia, R. Singh, A. Srivastava   +3 more
semanticscholar   +1 more source