Results 131 to 140 of about 586 (172)

Crystal structures of 4,11-pregnadiene-3,20-dione and 21-methyl-20-oxa-4-pregnene-3,20-dione

Journal of Chemical Crystallography, 1996
The structures of the title compounds were solved by direct methods and refined by anisotropic full-matrix least-squares methods. 4,11-Pregnadiene-3,20-dione, C21H28O2(1) crystallizes in the monoclinic space groupP21 (Z=2). The unit cell parametersa, b, c (A), and β (°) were: 12.319(2), 7.700(2), 9.717(2), 109.41(2).
Zdzislaw Wawrzak, Zdzisław Gałdecki, William L. Duax, Phyllis D. Strong, Pawel Grochulski, Ewa Gałdecka   +5 more
openaire   +2 more sources

New steroidal anti-inflammatory antedrugs: Methyl 3,20-dioxo-9α-fluoro-11β,17α,21-trihydroxy-1,4-pregnadiene-16α-carboxylate and methyl 21-acetyloxy-3,20-dioxo-11β,17α-dihydroxy-9α-fluoro-1,4-pregnadiene-16α-carboxylate

Steroids, 1997
Focused efforts have been made to increase local-to-systemic activity ratios of potent anti-inflammatory steroids for local and/or topical applications. The approach taken in the present investigation is based upon the concept of "antedrug," defined as a locally active compound that exerts its action at the application site but rapidly undergoes a ...
Ann S. Heiman, J.Lee Henry, Chen Meiqin, Dong-Hoon Ko   +3 more
openaire   +2 more sources

Notes: Synthesis of 1,4-Pregnadiene-17α,20α,21-triol-3,11-dione

The Journal of Organic Chemistry, 1959
R Beyler, L Sarett, Francis Hoffman
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A Natural Product That Lowers Cholesterol As an Antagonist Ligand for FXR

Science, 2002
Nancy L. Urizar, Amy D. B. Liverman, D. Dodds, Frank Valentin Silva, P. Ordentlich, Y. Yan, F. Gonzalez, R. Heyman, D. Mangelsdorf, D. Moore   +9 more
semanticscholar   +1 more source

Structures of the Isomeric 20-Hydroxy-4,16-Pregnadien-3-ones

The Journal of Organic Chemistry, 1964
Walter R. Benn, A. L. Nussbaum, R. Tiberi   +2 more
openaire   +2 more sources

3β-hydroxy-Δ5,16-Pregnadien-20-one from Veratrum grandiflorum

Phytochemistry, 1973
M. Watanabe, Koh Kaneko, Hiroshi Mitsuhashi   +2 more
openaire   +2 more sources

A Reinvestigation of the Synthesis of 5,16-Pregnadiene-3β,20α-diol. The Nuclear Magnetic Resonance Spectra of Some Epimeric 20-Hydroxypregnane Derivatives

, 1963
Walter R. Benn
openalex   +1 more source

The Addition of Ethanethiolic Acid to 3β-Acetoxy-5,16-pregnadien-20-one

The Journal of Organic Chemistry, 1965
Paul B. Sollman, J. R. Deason, Raymond M Dodson   +2 more
openaire   +2 more sources

The Polarographic Reduction of Prednisone (17α,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione), Prednisolone (11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione) and Their Precursors¹

Journal of the American Chemical Society, 1956
James. McGlotten, Peter. Kabasakalian
openaire   +2 more sources

X-ray study of budesonide: molecular structures and solid solutions of the (22S) and (22R) epimers of 11β,21-dihydroxy-16α,17α-propylmethylenedioxy-1,4-pregnadiene-3,20-dione

, 1978
J. Albertsson, Agneta Oskarsson, C. Svensson   +2 more
openalex   +1 more source