Results 11 to 20 of about 128 (107)

Lipid‐Regulating Effect of Traditional Chinese Medicine: Mechanisms of Actions

Evidence-Based Complementary and Alternative Medicine, Volume 2012, Issue 1, 2012., 2012
Traditional Chinese medicine (TCM) has been increasingly used for the treatment of dyslipidemia and cardiovascular disease. Recently, much progress has been made in studies on the mechanisms of action of the lipid‐regulating effect of TCM in animal experiments.
Wei-Jian Bei, Jiao Guo, Hai-Yun Wu, Yang Cao, Keji Chen   +4 more
wiley   +1 more source

Production of Prednisolone by Pseudomonas oleovorans Cells Incorporated Into PVP/PEO Radiation Crosslinked Hydrogels

BioMed Research International, Volume 2004, Issue 4, Page 219-226, 2004., 2004
In order to rise the yield of prednisolone from hydrocortisone, the Pseudomonas oleovorans cells were entrapped into radiation crosslinked poly (vinyl pyrrolidone)/poly(ethylene oxide) (PVP/PEO) hydrogel of different gel contents. The factors affecting the gel content and swelling behavior of the polymeric gel, such as polymer composition, polymer ...
Abeer Abd El-Hady, Hassan A. Abd El-Rehim   +1 more
wiley   +1 more source

Crystal Structure and Synthesis of 3.BETA.-Acetoxy-4,16-pregnadiene-6,20-dione

Analytical Sciences: X-ray Structure Analysis Online, 2004
C23H30O4 is orthorhombic, P212121. The unit-cell dimensions at 293 K are a = 6.0490(3), b = 12.7788(7), c = 26.8859(15)A, V = 2078.25(19)A3, Dx = 1.184 g/cm3, and Z = 4. The R value is R = 0.050 for 3663 reflections. The A, B, C and D rings occur in distorted half chair, distorted chair, distorted chair, and distorted envelope conformations.
SORIANO-GARCÍA, Manuel, VALENCIA, Norma, FLORES, Eugenio, BRATOEFF, Eugene, RAMÍREZ, Elena, CABEZA, Marisa   +5 more
openaire   +2 more sources

Efficient Synthesis of Steroidal Intermediates with a C17 Side Chain from Phytosterols by Genetically Modified Mycolicibacterium neoaurum NRRL B‐3805 Strain

ChemistryOpen, Volume 14, Issue 9, September 2025.
Two genetically modified strains are designed and constructed to produce 22‐hydroxy‐23,24‐bisnorchol‐4‐ene‐3‐one (4‐HBC) and 3‐oxo‐4,17‐pregnadiene‐20‐carboxylic acid methyl ester (PDCE) by disrupting and overexpressing the aldolase gene (thl) in the genetically modified strains of Mycolicibacterium neoaurum NRRL B‐3805, respectively, which are useful ...
Xuemei Li, Liangyan Zhu, Qiong Wu, Rui Zhang, Yiyin Liu, Na Liu, Jinhui Feng, Qiaqing Wu, Dunming Zhu   +8 more
wiley   +1 more source

Estudo físico-químico dos polimorfos da progesterona e estabilização da forma metaestável sobre matrizes poliméricas [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em FarmáciaA nucleação heterogênea induzida por polímeros (PIHn) é uma técnica inovadora utilizada no "screening" de polimorfos na ...
Sibaja, Andrea Mariela Araya
core  

Identification of the aldolase responsible for the production of 22‐hydroxy‐23,24‐bisnorchol‐4‐ene‐3‐one from natural sterols in Mycolicibacterium smegmatis

Microbial Biotechnology, Volume 17, Issue 1, January 2024.
We have identified the MSMEG_6561 gene, encoding an aldolase responsible for the transformation of 22‐hydroxy‐3‐oxo‐cholest‐4‐ene‐24‐carboxyl‐CoA (22‐OH‐BCN‐CoA) into the 22‐hydroxy‐23,24‐bisnorchol‐4‐ene‐3‐one (4‐HBC) precursor (20S)‐3‐oxopregn‐4‐ene‐20‐carboxaldehyde (3‐OPA).
Gabriel Hernández‐Fernández, Miguel G. Acedos, José L. García, Beatriz Galán   +3 more
wiley   +1 more source

Novel 17 Substituted Pregnadiene Derivatives as 5.ALPHA.-Reductase Inhibitors and Their Binding Affinity for the Androgen Receptor

Chemical and Pharmaceutical Bulletin, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Cabeza, Marisa, Flores, Eugenio, Heuze, Ivonne, Sánchez, Mauricio, Bratoeff, Eugene, Ramírez, Elena, Francolugo, Victor Alfonso   +6 more
openaire   +3 more sources

Crystal Structure and Synthesis of .BETA.-(p-Fluorobenzoyloxy)-4,16- pregnadiene-6,20-dione

Analytical Sciences: X-ray Structure Analysis Online, 2003
C28H31FO4 is monoclinic, P21. The unit-cell dimensions at 293 K are a = 12.4629(10), b = 6.1705(5), c = 15.5815(13)A, β = 102.243(2)°, V = 1171.00(17)A3, Dx = 1.278 g/cm3 and Z = 2. The R value is R = 0.048 for 4105 reflections. The A, B, C and D rings occur in half chair, distorted chair, distorted chair, and distorted envelope conformations.
SORIANO-GARCÍA, Manuel, VALENCIA, Norma, FLORES, Eugenio, BRATOEFF, Eugene, RAMÍREZ, Elena, CABEZA, Marisa   +5 more
openaire   +2 more sources

Urinary and biliary metabolites of 17.ALPHA.-acetoxy-6-chloro-4,6-pregnadiene-3,20-dione in the rabbit.

Chemical and Pharmaceutical Bulletin, 1974
Ten metabolites of 17α-acetoxy-6-chloro-4, 6-pregnadiene-3, 20-dione were isolated from urine and bile of the rabbit and their chemical structures were determined. The urinary main metabolite was 17α-acetoxy-2ξ, 3ξ-dihydroxy-5ξ-pregnan-20-one. The biliary main metabolite was 17α-acetoxy-6-chloro-2ξ, 3ξ-dihydroxy-4, 6-pregnadien-20-one. The administered
ABE, TATSUYA, KAMBEGAWA, AKIRA
openaire   +3 more sources

The Role of Myrrh Metabolites in Cancer, Inflammation, and Wound Healing: Prospects for a Multi-Targeted Drug Therapy. [PDF]

Pharmaceuticals (Basel), 2022
Suliman RS, Alghamdi SS, Ali R, Aljatli D, Aljammaz NA, Huwaizi S, Suliman R, Kahtani KM, Albadrani GM, Barhoumi T, Altolayyan A, Rahman I.   +11 more
europepmc   +1 more source