Results 101 to 110 of about 3,610,785 (264)

Antenatal interventions for reducing weight in obese women for improving pregnancy outcome

, 2013
Background: Being obese and pregnant is associated with substantial risks for the mother and her child. Current weight management guidance for obese pregnant women is limited.
Furber, Christine M., Kontopantelis, Evangelos, Bower, Peter, Lavender, Tina, Furber, C., McGowan, Linda, Kontopantelis, E, Bower, Peter; id_orcid, Furber, Christine M, Quenby, Siobhan, McGowan, L   +10 more
core   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Recurrent pregnancy loss, psychological distress and wellbeing support for women: a mixed-methods analysis

BMC Women's Health
Background Research suggests multiple experiences of miscarriage, also known as recurrent pregnancy loss (RPL), may be associated with compounded risk for adverse mental health impacts.
Áine Aventin, Martin Robinson, Jonathan White, Martina Galeotti   +3 more
doaj   +1 more source

Late-Term Elective Abortion and Susceptibility to Posttraumatic Stress Symptoms

Journal of Pregnancy, 2010
The primary aim of this study was to compare the experience of an early abortion (1st trimester) to a late abortion (2nd and 3rd trimester) relative to Posttraumatic Stress Disorder (PTSD) symptoms after controlling for socio-demographic and personal ...
Priscilla K. Coleman, Catherine T. Coyle, Vincent M. Rue   +2 more
doaj   +1 more source

A Clinical Study of Decellularized Tissue Engineering Hyaline Cartilage Graft (dLhCG) for Articular Cartilage Repair

Advanced Science, EarlyView.
ABSTRACT Current clinical approaches for knee cartilage repair are often limited by hypertrophy and fibrosis in the regenerated tissues. A decellularized tissue‐engineered hyaline cartilage graft (dLhCG), composed of a type II collagen‐based extracellular matrix, has been developed to overcome this limitation.
Zhen Zhang, Gong Cheng, Wenyong Fei, Qiuzhen Liang, Liang Zhang, Kegui Liu, Jihang Dai, Bo Cong, Xu Hu, Zhonglian Wu, Jialu Zhang, Jinlan Cui, Hang Yao, Dong‐An Wang, Jingcheng Wang, Tao Sun, Jiang Zheng   +16 more
wiley   +1 more source

Thrombotic thrombocytopenic purpura and pregnancy: presentation, management, and subsequent pregnancy outcomes

, 2014
Pregnancy can precipitate thrombotic thrombocytopenic purpura (TTP). We present a prospective study of TTP cases from the United Kingdom Thrombotic Thrombocytopenic Purpura (UK TTP) Registry with clinical and laboratory data from the largest cohort of ...
Camilleri, Raymond S., Ni Ainle, F., Camilleri, R., McGuckin, S., Underwood, M., Thomas, M., Watson, H., Evans, G., Lester, W., Scott, R., O Brien P; collaborators of the UK TTP Registry, Scully, M., McDonald, V., Maclean, R., O Brien, P., Clark, A., Rayment, R., Langley, K., Roy, A., Creagh, D., Nash, M.   +20 more
core   +1 more source

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source

Pregnancy happiness: implications of prior loss and pregnancy intendedness [PDF]

, 2020
Objective: This study aimed to examine the interaction between pregnancy loss and pregnancy intentions on women’s happiness about a subsequent pregnancy. Background: Anxiety about prior loss persist for women, even during subsequent pregnancies.
Tiemeyer, Stacy, Shreffler, Karina, McQuillan, Julia   +2 more
core  

Medication exposure during pregnancy: a pilot pharmacovigilance system using health and demographic surveillance platform [PDF]

, 2014
There is limited safety information on most drugs used during pregnancy. This is especially true for medication against tropical diseases because pharmacovigilance systems are not much developed in these settings.
Abdulla, Salim, Mrema, Sigilbert, Mosha, Dominic, Mazuguni, Festo, Genton, Blaise, Mazuguni, F., Abdulla, S., Genton, B., Mosha, D., Mrema, S.   +9 more
core   +1 more source