Results 91 to 100 of about 3,433,369 (265)

Late-Term Elective Abortion and Susceptibility to Posttraumatic Stress Symptoms

Journal of Pregnancy, 2010
The primary aim of this study was to compare the experience of an early abortion (1st trimester) to a late abortion (2nd and 3rd trimester) relative to Posttraumatic Stress Disorder (PTSD) symptoms after controlling for socio-demographic and personal ...
Priscilla K. Coleman, Catherine T. Coyle, Vincent M. Rue   +2 more
doaj   +1 more source

Hydrophilic Polymers Enable Gastrointestinal Transit Monitoring by Fluorine‐19 Magnetic Resonance Imaging

Advanced Healthcare Materials, EarlyView.
Hydrophilic fluorinated copolymers dissolve in chyme and give a strong, single 19F signal, unlike phase‐separating perfluorocarbons. Combined 1H‐19F MRI tracks their whole‐gut transit non‐invasively and without ionizing radiation. In rats, the tracers move through the gastrointestinal tract, resist resorption, and are well tolerated, a proof‐of‐concept
Ondřej Groborz, Vít Herynek, Mária Hovořáková, Zuzana Pavlíková, Linda Dalecká, Klára Steklíková, Petr Matouš, Petr Páral, Margarita Tkachenko, Filip Koucký, Fatma Nalan Cetin, Ludmila Maffei Svobodová, Jiří Beneš, Kristýna Kolouchová   +13 more
wiley   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Malaria in pregnancy: the difficulties in measuring birthweight [PDF]

, 2011
Recommendations for interventions to control malaria in pregnancy are often based on studies using birthweight as the primary endpoint. Differences in birthweight may be attributable partly to methodological difficulties. We performed a structured search
F Nosten, AT Papageorghiou, Nosten, F., Rijken, JA, JA Rijken, McGready, R, Papageorghiou, A. T., Kennedy, S. H., McGready, R., GHA Visser, Visser, GH, Visser, G. H. A., Kennedy, SH, Rijken, M. J., Mcgready, Rose, R McGready, SH Kennedy, Rijken, MJ, Rijken, J. A., Nosten, F, Papageorghiou, AT, Kennedy, Stephen, MJ Rijken   +22 more
core   +1 more source

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐Shielded Heart Valves

Advanced Healthcare Materials, EarlyView.
Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk, Leanne Van den Berg, Isa B. M. Velraeds, Valentina Osorio Zuluaga, Emma T. M. Peereboom, Martijn J. W. E. Rabelink, Arnaud Zaldumbide, Rob C. Hoeben, Marie‐Jose T. H. Goumans, Eric Spierings, Carlijn V. C. Bouten, Marijn C. Peters   +11 more
wiley   +1 more source

Chemical Screening Identifies Danofloxacin as a Self‐Renewal Agonist of Embryonic Stem Cells through Alleviation of HDAC1‐Mediated Deacetylation of Tert and Prdm10

Advanced Science, EarlyView.
This study identified Danofloxacin as a novel supporter of the maintenance of mouse embryonic stem cell (ESC) pluripotency. It functions partially by inhibiting HDAC1, which increases specific histone acetylation marks and activates key genes like Tert and Prdm10.
Yan Zhang, Junxiang Ji, Baoxing Dong, Zhenhua Zhu, Xucheng Lv, Peng Chen, Wenqiang Liu, Min Zhou, Shou‐Dong Ye   +8 more
wiley   +1 more source

Publisher Correction to: Developing guideline-based key performance indicators for recurrent miscarriage care: lessons from a multi-stage consensus process with a diverse stakeholder group

Research Involvement and Engagement, 2022
Marita Hennessy, Laura Linehan, Rebecca Dennehy, Declan Devane, Rachel Rice, Sarah Meaney, Keelin O’Donoghue   +6 more
doaj   +1 more source

Pregnancy loss and mental health

, 2011
Between 8 and 20 percent of depression in young men and women aged 18-23 is associated with pregnancy loss, according to a recent analysis of the 30 year Mater Hospital longitudinal study of mothers and children.\ud \ud Dr Kaeleen Dingle from the ...
Dingle, Kaeleen D.
core  

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Maternity staff views on implementing a national perinatal mortality review tool: understanding barriers and facilitators

Journal of Perinatal Medicine
Perinatal death reviews investigate the causes of perinatal mortality, identify potentially avoidable factors, and may help prevent further deaths. This study aimed to identify barriers and facilitators to the implementation of a standardised perinatal ...
O’Connor Emily, Helps Aenne, Greene Richard, O’Donoghue Keelin, Leitao Sara   +4 more
doaj   +1 more source