Results 121 to 130 of about 314,865 (313)

SLC6A14 Drives Mitochondrial Fusion and Oxidative Phosphorylation to Promote Cancer Stemness and Early‐Onset of Breast Cancer

Advanced Science, EarlyView.
Elevated levels of the plasticizer DEHP associate with earlier breast cancer diagnosis. DEHP enhances glutamine‐powered energy production via the transporter SLC6A14 and pushes mitochondria toward fusion, driving tumor initiation by boosting cancer stemness. Blocking SLC6A14 lowers stemness, slows tumors, and improves chemotherapy response.
Dai‐Wei Hu, Chih‐Hao Huang, Yu‐Hao He, Ya‐Ling Wei, Shu‐Wei Hu, Fang‐Ju Cheng, Thanh Kieu Huynh, Bo‐Rong Chen, Bo‐Wei Wang, Li‐Chi Kuan, Der‐Yen Lee, Ming‐Hsin Yeh, Ya‐Jen Chang, Liang‐Chih Liu, Mien‐Chie Hung, Wei‐Chien Huang   +15 more
wiley   +1 more source

Systematic description of the development of a complex health intervention of information and support in a new pregnancy after pregnancy loss

BMC Public Health
Background In this paper, we present a systematic description of the development method of a complex health intervention (PREGAFTERPL) for couples with prior pregnancy loss (PL) to provide information and support in a new pregnancy using co-production ...
Emily Koert, Sarah Fredsted Villadsen, Rebecca Mackel, Helene Cagara, Tanja Schlaikjær Hartwig, Henriette Svarre Nielsen, Lone Schmidt   +6 more
doaj   +1 more source

Detection of Anti-Annexin V Antibodies in Recurrent Pregnancy Loss [PDF]

, 2000
Hidehiko Matsubayashi, Tadashi Arai, Shun‐ichiro Izumi, Tsunehisa Makino, John A. McIntyre   +4 more
openalex   +1 more source

Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells

Advanced Science, EarlyView.
This study revealed that epithelial cancer cells in the floating phase induce the expression of laeverin (LVRN) that is a trophoblast‐specific and cell‐surface immunoregulatory factor and showed that anti‐LVRN ADC is a promising agent that can attack cancer cells in the metastatic liquid phase and block further distant metastasis.
Haruki Kasama, Yuya Sakai, Kyosuke Kagami, Takashi Iizuka, Tatsuhito Kanda, Takuma Suzuki, Kayo Kayahashi, Masanori Ono, Tomoko Fujiwara, Shintaro Yagi, Noriyuki Inaki, Isao Matsumoto, Rena Yamazaki, Kaoru Abiko, Noriomi Matsumura, Akira Hattori, Takiko Daikoku, Hiroshi Fujiwara   +17 more
wiley   +1 more source

T Helper 1 (Th1) Immunity to Trophoblast in Women with Recurrent Pregnancy Loss (RPL) Is Associated with a Variant in the IL1B Promoter Region [PDF]

, 2000
Z.C Wang, Edmond J. Yunis, Ling Xiao, Ma José de los Santos, Deborah J. Anderson, Jonathan A. Hill   +5 more
openalex   +1 more source

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Advanced Science, EarlyView.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source

Author's reply – Intravenous immunoglobulin treatment in women with four or more recurrent pregnancy losses: A double-blind, randomised, placebo-controlled trial

EClinicalMedicine, 2022
Hideto Yamada, Masashi Deguchi, Shigeru Saito, Toshiyuki Takeshita   +3 more
doaj   +1 more source

Novel Role of Gut‐Derived Roseburia Intestinalis in Safeguarding Intestinal Barrier Integrity and Microenvironment Homeostasis During Arsenic Exposure

Advanced Science, EarlyView.
Arsenic exposure disrupts intestinal barriers and gut microenvironment. Fecal microbiota transplantation (FMT) alleviates arsenic‐induced damage, with gut‐derived Roseburia intestinalis (R.i) identified as a key protective strain. R.i administration counters arsenic toxicity through immunomodulatory pathways and metabolites.
Lixiao Zhou, Chunsong Wang, Jieying Gao, Xu Wu, Geng Li, Xuejun Jiang, Yinyin Xia, Jun Zhang, Bo Lv, Feng Zhao, Hongyang Zhang, Huifeng Pi, Jingfu Qiu, Shangcheng Xu, Zhen Zou, Chengzhi Chen   +15 more
wiley   +1 more source

Blood loss during first trimester termination of pregnancy: comparison of two anaesthetic techniques

, 1997
James Edwin Hall, W. S. Ng, Saxon D. Smith   +2 more
openalex   +1 more source

Preferential X-chromosome inactivation in women with idiopathic recurrent pregnancy loss [PDF]

, 2001
Shigeki Uehara, Masaki Hashiyada, Kazuyo Sato, Yumi Sato, Keiya Fujimori, Kunihiro Okamura   +5 more
openalex   +1 more source