Results 21 to 30 of about 770,380 (355)

A combination of the HLA-DRB1*03 phenotype and low plasma mannose-binding lectin predisposes to autoantibody formation in women with recurrent pregnancy loss

Frontiers in Immunology, 2023
IntroductionIt is documented that a series of autoantibodies can be detected with increased frequency in women with recurrent pregnancy loss (RPL) and they may impact the pregnancy prognosis negatively.
Caroline Nørgaard-Pedersen, Caroline Nørgaard-Pedersen, Rudi Steffensen, Ulrik Schiøler Kesmodel, Ulrik Schiøler Kesmodel, Ole Bjarne Christiansen, Ole Bjarne Christiansen   +6 more
doaj   +1 more source

Caffeine Inhibits EGF-Stimulated Trophoblast Cell Motility through the Inhibition of mTORC2 and Akt. [PDF]

, 2012
Impaired trophoblast invasion is associated with pregnancy disorders such as early pregnancy loss and preeclampsia. There is evidence to suggest that the consumption of caffeine during pregnancy may increase the risk of pregnancy loss; however, little is
Alison E. Wallace, Bauer, Beavo, Biadasiewicz, Boulbes, Brent, Brooke Lumicisi, Brosens, Burton, CARE Study Group, Cartwright, Cartwright, Cartwright, Chui, Di Fiore, Fabro, Foukas, Goldstein, Gude, Guy S. Whitley, Hofmann, Isobelle Grant, Jang, Judith E. Cartwright, Julien, LaMarca, LaMarca, LaMarca, Lee, Liu, Marone, Maslova, Mei, Olayioye, Omori, Pollheimer, Robertson, Spindle, Stefanidou, Tsygankova, Wadge, Weng, Yarden, Yarden, Yoshino, Zhang, Zoncu   +46 more
core   +1 more source

Uterine NK cells are critical in shaping DC immunogenic functions compatible with pregnancy progression. [PDF]

, 2012
Dendritic cell (DC) and natural killer (NK) cell interactions are important for the regulation of innate and adaptive immunity, but their relevance during early pregnancy remains elusive.
Burghard F. Klapp, Elke Winterhager, Gabriela Barrientos, Irene Tirado González, Nancy Freitag, Petra Moschansky, Petra von Kwiatkowski, Sandra M. Blois, Stefan Bauersachs, Teresa Otto, Victor L. J. L. Thijssen, Yan-Ling Wang   +11 more
core   +7 more sources

University students’ awareness of causes and risk factors of miscarriage: a cross-sectional study

BMC Women's Health, 2018
Background Spontaneous miscarriage is the most common complication of pregnancy, occurring in up to 20% of pregnancies. Despite the prevalence of miscarriage, little is known regarding peoples’ awareness and understanding of causes of pregnancy loss. The
Indra San Lazaro Campillo, Sarah Meaney, Jacqueline Sheehan, Rachel Rice, Keelin O’Donoghue   +4 more
doaj   +1 more source

Facilitators and barriers influencing weight management behaviours during pregnancy: a meta-synthesis of qualitative research

BMC Pregnancy and Childbirth, 2022
Background Obesity and overweight are considered risk factors for a range of adverse outcomes, including stillbirth. This study aims to identify factors reported by women influencing weight management behaviours during pregnancy.
Tamara Escañuela Sánchez, Sarah Meaney, Caroline O’Connor, Laura Linehan, Keelin O’Donoghue, Molly Byrne, Karen Matvienko-Sikar   +6 more
doaj   +1 more source

A protocol for a systematic review of behaviour change techniques used in the context of stillbirth prevention [version 2; peer review: 2 approved, 1 approved with reservations]

HRB Open Research, 2022
Background: Stillbirth is a devastating pregnancy outcome that affects approximately 3.5 per 1000 births in high-income countries. Previous research has highlighted the importance of focusing prevention efforts on targeting risk factors and vulnerable ...
Molly Byrne, Keelin O'Donoghue, Sarah Meaney, Tamara Escañuela Sánchez, Karen Matvienko-Sikar   +4 more
doaj   +1 more source

Circulating levels of matrix proteases and their inhibitors in pregnant women with and without a history of recurrent pregnancy loss [PDF]

, 2010
Background: We have recently shown that serum relaxin-2 levels are attenuated in women with a history of recurrent pregnancy loss (RPL). We sought to determine whether a history of RPL is also associated with changes in serum matrix metalloproteases ...
Anumba, D.O.C., El Gelany, S., Elliott, S.L., Li, T.C.   +3 more
core   +3 more sources

Parents and clinicians: partners in perinatal bereavement research –experiences from the International Stillbirth Alliance Conference 2017

Research Involvement and Engagement, 2019
In recent years, there has been a global call to reduce the numbers of preventable stillbirths and increase public awareness about the incidence and impact of pregnancy loss. The lived experiences of bereaved parents have much to contribute to developing
Rachel Rice, Daniel Nuzum, Orla O’Connell, Keelin O’Donoghue   +3 more
doaj   +1 more source

Autoimmune lymphoproliferative syndrome in pregnancy: a case of favorable mother - fetal outcome in a well-controlled disease [PDF]

, 2014
The autoimmune lymphoproliferative syndrome(ALPS)is a disorder of abnormal lymphocyte survival caused by the dysregulation of theFasapoptotic pathway. The Fas geneis expressed at the maternal–fetal interface and is involved in the regulation of immune ...
Baek, Bleesing, Canale, Ciarmela, Correia-da-Silvia, Ferguson, Fuks, Hansford, Jerzak, Kwak-Kim, Lev, Oliveira, Rao, Rogers, Worth   +14 more
core   +1 more source

Gene Expression Profiling of Corpus luteum Reveals Important Insights about Early Pregnancy in Domestic Sheep [PDF]

, 2020
The majority of pregnancy loss in ruminants occurs during the preimplantation stage, which is thus the most critical period determining reproductive success. Here, we performed a comparative transcriptome study by sequencing total mRNA from corpus luteum
Honkatukia, Mervi, Kantanen, Juha, Li, Meng-Hua, Peippo, Jaana, Pokharel, Kisun, Weldenegodguad, Melak   +5 more
core   +1 more source