Results 41 to 50 of about 357,374 (288)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala +8 more
wiley +1 more source
Current Irish medicolegal landscape: an unsustainable trajectory
BMJ Open Quality, 2023 The number of outstanding clinical claims that are yet to be resolved as well as their associated estimated costs are at a record high in Ireland. By the end of 2022, the Irish government face 3875 active clinical claims which are expected to cost €3.85 ...
Keelin O'Donoghue +3 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Journal of Assisted Reproduction and GeneticsPregnancy loss is the most common obstetric complication occurring in almost 15% of pregnancies. Of the examined products of conception (POC), approximately 60% of pregnancy losses result from chromosomal abnormalities and copy number variations (CNVs) in embryos, but genetic etiologies of euploid pregnancy loss remain largely unexplained.
Tatiana V. Nikitina +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Selenium levels and recurrent pregnancy loss : is there an association? [PDF]
, 2010 Includes abstract.Includes bibliographical references (leaves 58-67).Miscarriage is the commonest complication of pregnancy and affects 12-31% of all conceptions.
Thomas, Viju
core
"Making it all normal" : the role of the internet in problematic pregnancy [PDF]
, 2009 Women are actively encouraged to educate themselves about pregnancy from formal sources (e.g., information leaflets, antenatal classes, books). In addition, informal stories of pregnancy and birth are routinely told between women.
Locock, Margaret +8 more
core +1 more source
Miscarriage hospitalisations: a national population-based study of incidence and outcomes, 2005–2016
Reproductive Health, 2019 Background Early miscarriage is one of the most common obstetric causes of maternal morbidity early in pregnancy. However, data concerning non-fatal complications among hospitalisations for early miscarriage are lacking.
Indra San Lazaro Campillo +3 more
doaj +1 more source
BMC Pregnancy and Childbirth, 2023 Objective This review aimed to identify guidelines with recommendations applicable to the antenatal management of dichorionic diamniotic twin pregnancies within high-income countries, appraise their methodological quality, and discuss the similarities ...
Caroline O’Connor +4 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 Physiological hormonal fluctuations exert endogenous pressures on the structure and function of the human microbiome. As such, the menstrual cycle may selectively disrupt the homeostasis of the resident oral microbiome, thus compromising oral health ...
Nagihan Bostanci +19 more
doaj +1 more source