Results 51 to 60 of about 357,374 (288)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Recurrent pregnancy loss: current perspectives [PDF]

, 2017
Hady El Hachem,1,2 Vincent Crepaux,3 Pascale May-Panloup,4 Philippe Descamps,3 Guillaume Legendre,3 Pierre-Emmanuel Bouet3 1Department of Reproductive Medicine, Ovo Clinic, Montréal, QC, Canada; 2Department of Obstetrics and Gynecology ...
El Hachem H, Legendre G, Crepaux V, Bouet PE, May-Panloup P, Descamps P   +5 more
core  

Immune system function, stress, exercise and nutrition profile can affect pregnancy outcome: Lessons from a Mediterranean cohort [PDF]

, 2013
This article is made available through the Brunel Open Access Publishing Fund.Pregnancy is associated with major physiological and future psychosocial changes, and maternal adaptation to these changes is crucial for normal foetal development ...
Karteris, E, Zachariades, E, Goumenou, A, Gidron, Y, Pados, G, Mparmpakas, D   +5 more
core   +1 more source

Recurrent Miscarriage and Infertility Services and Supports: A Qualitative Study of Views and Experiences in the Republic of Ireland

Health Expectations
Background Recurrent miscarriage (RM) and infertility are separately associated with psychological distress and adverse pregnancy outcomes. The dual experience is devastating for women/couples but is not considered in clinical guidance for RM or ...
Laura Aoife Linehan, Marita Hennessy, Keelin O'Donoghue   +2 more
doaj   +1 more source

Advances in the diagnosis and early management of gestational trophoblastic disease

BMJ Medicine, 2022
Gestational trophoblastic disease describes a group of rare pregnancy related disorders that span a spectrum of premalignant and malignant conditions. Hydatidiform mole (also termed molar pregnancy) is the most common form of this disease.
Keelin O'Donoghue, Brendan Fitzgerald, John Coulter, Caroline M Joyce, Tommie V McCarthy   +4 more
doaj   +1 more source

Visual loss in pregnancy

BMJ Case Reports, 2019
Visual loss in pregnancy may be caused by a variety of reasons including pituitary adenomas. Prolactinomas (PRLs) are the most common hormone-secreting tumours in pregnant women. As most PRLs present with menstrual abnormalities, infertility or galactorrhoea, they are most commonly diagnosed before pregnancy.
Bachmeier, Caroline Annette Erika, Snell, Cameron, Morton, Adam   +2 more
openaire   +6 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Time to pregnancy : a computational method for using the duration of non-conception for predicting conception [PDF]

, 2012
An important problem in reproductive medicine is deciding when people who have failed to become pregnant without medical assistance should begin investigation and treatment. This study describes a computational approach to determining what can be deduced
Geraldine M Hartshorne, Hartshorne Geraldine M., Sozou, Peter D., Geraldine M. Hartshorne (129593), Peter D. Sozou (129592), Sozou Peter D., Hartshorne, Geraldine M., Peter D Sozou, Sozou, Peter   +8 more
core   +1 more source

Artificial placentas, pregnancy loss and loss-sensitive care [PDF]

, 2023
In this paper, we explore how the prospect of artificial placenta technology (nearing clinical trials in human subjects) should encourage further consideration of the loss experienced by individuals when their pregnancy ends unexpectedly.
Adkins, Victoria, Romanis, Elizabeth Chloe   +1 more
core   +2 more sources

Involving Knowledge Users in Health Services Research: Collective Reflections and Learning From a National Evaluation of Recurrent Miscarriage Services

Health Expectations
Introduction Involving knowledge users in research can facilitate the translation of evidence into policy and practice. How to best involve and support various types of knowledge users, including patient and public involvement contributors, in research ...
Marita Hennessy, Rebecca Dennehy, Hannah O'Leary, Keelin O'Donoghue, RE:CURRENT Research Advisory Group   +4 more
doaj   +1 more source