Results 31 to 40 of about 3,433,369 (265)

Can Recurrent Pregnancy Loss Be Prevented by Antithrombotic Agents?

, 2020
Antithrombotic agents encompass two classes of drugs: antiplatelet agents and anticoagulant agents. Antiplatelet agents prevent platelets from aggregating and forming blood clots.
Paidas, Michael J, Audrey A. Merriam, Michael J. Paidas, Merriam, Audrey A   +3 more
core   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Current Irish medicolegal landscape: an unsustainable trajectory

BMJ Open Quality, 2023
The number of outstanding clinical claims that are yet to be resolved as well as their associated estimated costs are at a record high in Ireland. By the end of 2022, the Irish government face 3875 active clinical claims which are expected to cost €3.85 ...
Keelin O'Donoghue, Clara Forrest, Dearbhaile C Collins, Seamus O'Reilly   +3 more
doaj   +1 more source

Mixed methods research of crisis pregnancy counselling and support services [PDF]

, 2005
This study aimed to examine women’s experiences of crisis pregnancy counselling using both qualitative and quantitative methods. The study group comprised women with a crisis pregnancy who either decided on abortion or were continuing the pregnancy ...
Conlon, Catherine
core  

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Irish contraception and crisis pregnancy [ICCP] study: a survey of the general population - summary [PDF]

, 2004
The aim of the present study was to establish nationally representative data on current attitudes, knowledge and experience of contraception, crisis pregnancy and related services in Ireland.
McGee, Hannah, Leigh, Collette, Rundle, Kay, Layte, Richard   +3 more
core  

Men, trans/masculine, and non-binary people's experiences of pregnancy loss: an international qualitative study. [PDF]

, 2020
Growing numbers of men, trans/masculine, and non-binary people are becoming gestational parents, yet very little is known about experiences of pregnancy loss among this diverse population. The study employed a cross sectional design.
Pfeffer, Carla A., Hines, S., Ruspini, Elisabetta, Ruspini, E., White, Francis Ray, Pearce, Ruth, Riggs, D.W., Pearce, R., White, F.R., Pfeffer, C.A., Hines, Sally, Riggs, Damien W.   +11 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Miscarriage hospitalisations: a national population-based study of incidence and outcomes, 2005–2016

Reproductive Health, 2019
Background Early miscarriage is one of the most common obstetric causes of maternal morbidity early in pregnancy. However, data concerning non-fatal complications among hospitalisations for early miscarriage are lacking.
Indra San Lazaro Campillo, Sarah Meaney, Keelin O’Donoghue, Paul Corcoran   +3 more
doaj   +1 more source

Clinical practice guidelines for the antenatal management of dichorionic diamniotic twin pregnancies: a systematic review

BMC Pregnancy and Childbirth, 2023
Objective This review aimed to identify guidelines with recommendations applicable to the antenatal management of dichorionic diamniotic twin pregnancies within high-income countries, appraise their methodological quality, and discuss the similarities ...
Caroline O’Connor, Emily O’Connor, Sara Leitao, Shauna Barrett, Keelin O’Donoghue   +4 more
doaj   +1 more source