Results 171 to 180 of about 11,486 (263)

First Report of Co‐Inheritance of Hemoglobin British Columbia (HBB:c.304G>A) and β‐Thalassemia IVS‐I‐6 (HBB:c.92+6T>C): Clinical Characterization of an Iranian Case

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
ABSTRACT Background Hemoglobin British Columbia is a rare high‐oxygen‐affinity β‐globin variant caused by the HBB:c.304G>A substitution. Its detection is exceptionally uncommon, particularly in the Middle East, and may lead to diagnostic pitfalls when relying solely on hemoglobin separation techniques.
Kimia Fathalizade   +5 more
wiley   +1 more source

Pregnancy Associated Melanoma: Diagnostic and Therapeutic Challenges. [PDF]

open access: yesMedicina (Kaunas)
Atanasescu VP   +7 more
europepmc   +1 more source

Performance Evaluation of a Premier Resolution HPLC System for Detecting Hemoglobin Constant Spring, Hemoglobin Paksé, and Coexisting α‐ and β‐Thalassemia Mutations

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study compared Premier Resolution HPLC with Capillary Electrophoresis for detecting HbCS/Hb Paksé variants and coexisting thalassemia mutations. Premier Resolution HPLC demonstrated superior performance with 50% fewer false negative cases (11 vs. 22) compared to Capillary Electrophoresis, particularly in heterozygous cases.
Surada Satthakarn   +2 more
wiley   +1 more source

Clinical significance of plasma SERPINA3 in patients with missed miscarriage. [PDF]

open access: yesFront Med (Lausanne)
Jiang Y   +10 more
europepmc   +1 more source

Age‐Associated Variations in Complete Blood Cell Count Parameters and Derived Indices Among Community‐Dwelling Chinese Older Adults

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This cross‐sectional study analyzed data from 9331 participants aged 24–97 to characterize age‐ and sex‐related physiological trajectories of complete blood cell count (CBC) parameters and derived inflammatory indices. Key findings encompassed age‐related declines in red blood cell and platelet counts, elevations in RDW‐CV indices and monocyte ...
Xiangyi Ma   +8 more
wiley   +1 more source

Serum Apelin‐13 and Galectin‐3 in COVID‐19: Associations With Routine Biochemical Parameters and Diagnostic Performance in a Case–Control Study

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Serum Apelin‐13 and Galectin‐3 levels were measured by ELISA in COVID‐19–positive patients and controls and evaluated alongside routine biochemical parameters. COVID‐19 patients showed significant alterations in liver, renal, inflammatory, and metabolic markers.
İsmail Uğurlu
wiley   +1 more source

Reference Interval Establishment for Four Coagulation Parameters Using Indirect Methods in a High‐Altitude Chinese Population: A Retrospective Real‐World Analysis

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study established reference intervals for APTT, PT, TT, and FIB in a Tibetan high‐altitude population using two indirect algorithms, Hoffmann and refineR. The established RIs differed significantly from those of low‐altitude regions, highlighting the need for region‐specific RIs to ensure accurate evaluation of coagulation disorders.
Banjiu Zhaxi   +15 more
wiley   +1 more source

Postpartum Ischemic Stroke As the First Manifestation of Late-Onset Preeclampsia: A Case Report. [PDF]

open access: yesCureus
Benaini I   +6 more
europepmc   +1 more source

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