Results 181 to 190 of about 11,486 (263)

Soluble B7‐H6 as a Novel Diagnostic Biomarker for Post‐Hepatitis B Cirrhosis: A Clinical Value Study

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study investigates the potential of soluble B7‐H6 (sB7‐H6) as a novel diagnostic biomarker for post‐hepatitis B cirrhosis. The infographic visually presents the following key points: (1) Liver Disease Progression: Chronic hepatitis B (CHB) progresses to liver cirrhosis (LC), with serum sB7‐H6 levels increasing stepwise as the disease advances. (2)
Kaiyong Chen   +4 more
wiley   +1 more source

Resolving a Complex Neonatal Phenotype by Rapid Trio Whole‐Genome Sequencing: A De Novo 11q14.3–q22.3 Deletion and a Splicing‐Altering Synonymous ANK1 Variant

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Clinical utility of trio WGS and time metrics in a neonate with congenital anomalies and hemolytic anemia. ABSTRACT Background Neonates with complex and evolving phenotypes often lack sufficiently specific clinical features to guide targeted genetic testing.
Hyun‐Woo Lee   +8 more
wiley   +1 more source

Preliminary Evaluation of a Novel Lupus Anticoagulant Activity Assay Unaffected by Anticoagulants

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
A novel one‐step lupus anticoagulant (LA) assay based on the LA‐sensitivity ratio (LA‐SR) was developed to simplify diagnostic testing and reduce potential interference from anticoagulants. The LA‐SR method showed good agreement with guideline‐based LA testing (dRVVT and/or LA‐sensitive APTT) for the detection of LA and demonstrated limited influence ...
Ayu Hidaka   +4 more
wiley   +1 more source

Characterization of Pulmonary Functional Abnormalities in Systemic Sclerosis Using Xenon MRI

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Xenon MRI is increasingly used to evaluate patients with interstitial lung disease (ILD) and pulmonary hypertension (PH), both of which are common manifestations of systemic sclerosis (SSc). As such, Xe‐MRI may be suited to interrogate lung function impairment in SSc.
Dawson Shaver   +11 more
wiley   +1 more source

Identification of Maternal Serum Longitudinal Signatures Through Profiling of 96 Cytokines. [PDF]

open access: yesLife (Basel)
Kolesnyk V   +10 more
europepmc   +1 more source

Immunomodulators, associated or not with systemic antibiotics, to treat periodontitis: A 1‐year multicenter, placebo‐controlled, double‐blind, randomized clinical trial

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Immunomodulatory agents such as omega‐3 (ω‐3) and low‐dose aspirin (ASA) have been proposed as effective adjuncts in the treatment of periodontitis. However, they still lack long‐term studies and head‐to‐head evaluation with metronidazole (MTZ) and amoxicillin (AMX), the adjunct protocol with the strongest scientific evidence of ...
Nidia C. Castro dos Santos   +14 more
wiley   +1 more source

Early pregnancy is characterized by a significant decrease in the diversity of the oral microbiome and strong associations with lifestyle and conception method. [PDF]

open access: yesJ Oral Microbiol
Finkelstein S   +19 more
europepmc   +1 more source

Surveying immune and inflammatory alterations in periodontitis among individuals with Down syndrome: A preliminary cross‐sectional study

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Individuals with Down syndrome (DS) are particularly vulnerable to early‐onset and rapidly progressing periodontitis, yet the local immune‐inflammatory alterations that contribute to this susceptibility are not fully understood. This study aimed to characterize cytokine profiles in gingival crevicular fluid (GCF) from individuals ...
Leticia Helena Theodoro   +7 more
wiley   +1 more source

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