Results 71 to 80 of about 641,577 (269)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Exploring Experiences with “321” Model Management for High-Risk Pregnancy: A Qualitative Study

Maternal-Fetal Medicine, 2023
Wen Sun, Peili Du, Lin Yu, Xiaoyi Wang, Fang He, Jingsi Chen, Chunhong Su, Dunjin Chen   +7 more
doaj   +1 more source

HIV risk perception and associated factors among pregnant and breastfeeding women in Zambia: implications for PrEP uptake in antenatal and postnatal settings

Frontiers in Reproductive Health
IntroductionHIV risk perception is seen as a key motivation for individuals to use biomedical HIV prevention interventions, including pre-exposure prophylaxis (PrEP).
Twaambo Euphemia Hamoonga, Wilbroad Mutale, Karen Hampanda, Benjamin H. Chi   +3 more
doaj   +1 more source

Congenital defects of development – contribution to children’s morbidity and disability, approaches to prevention

Репродуктивная эндокринология, 2018
One of the most important reasons for the formation of structural anomalies during the prenatal period is the lack of nutrients in the diet of a pregnant woman, such as folates, iodine and docosahexaenoic acid.
О. И. Пикуза, А. М. Закирова, Е. В. Волянюк, Ф. Ф. Ризванова   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The Epidemiology, Associated Factors and Bacterial Profile of Asymptomatic Bacteriuria in Pregnant Women: A Retrospective Chart Review Study in Saudi Arabia

International Journal of Women's Health, 2022
Nouf A AlShamlan,1 Reem S AlOmar,1 Roba Aldossary,2 Maha Alahmari,2 Asma Alghamdi,2 Mawaddah AlGhamdi,2 Najla Alkanaan,2 Abdullah H AlReedy,1 Amani S AlOtaibi,3 Nada S Alghamdi4 1Department of Family and Community Medicine, College of Medicine, Imam ...
AlShamlan NA, AlOmar RS, Aldossary R, Alahmari M, Alghamdi A, AlGhamdi M, Alkanaan N, AlReedy AH, AlOtaibi AS, Alghamdi NS   +9 more
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Pregnant smokers: Room for improvement [PDF]

Clinical Health Promotion - Research and Best Practice for patients, staff and community, 2015
Contact: Hanne Tonnesen Hanne.Tonnesen@regionh.dk Overall, the effect of smoking cessation intervention for pregnant women is as low as 6% (5). The more effective programmes include incitements (5) and intensive interventions over 6 weeks (6). The 6 weeks Gold Standard Programme is implemented as the standard intervention in Denmark and has recently ...
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source