Results 61 to 70 of about 1,191,573 (331)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Clinical manifestations comparison in hospitalized pregnant and non-pregnant women with Covid-19 at Mataram University Hospital, Mataram, Indonesia

open access: yesMajalah Obstetri dan Ginekologi, 2022
HIGHLIGHTS 1. Clinical manifestations in pregnant and non-pregnant women with Covid-19 were identified. 2. Pregnant women with Covid-19 mostly had asymptomatic clinical manifestations, while non-pregnant women with Covid-19 mostly had symptomatic ...
Putu Diah Ananda Putri Atmaja   +2 more
doaj   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Investigating the Relationship Between Mental Health and Insomnia in Pregnant Women Referred to Health Centers in Estahban [PDF]

open access: yes, 2015
Pregnancy is the most sensitive period in women's life which makes many physical and mental changes. Sleep problems are one of the issues that are reported by pregnant women; it appears to be associated with psychological consequences in pregnant women ...
Babaie, N. A. (Naemeh)   +1 more
core  

Elimination of Congenital Syphilis in Ukraine: Analysis and the Emerging Issues [PDF]

open access: yes, 2017
The objective of this study is to analyze the indicators of the process of elimination of mother-to-child transmission of syphilis in Ukraine thus helping to prepare for elimination of this process according to the WHO targets and criteria ...
Derevyanko, L. (Lyudmyla)
core   +2 more sources

Possible mechanisms involved in improved beta cell function in pregnant women with type 1 diabetes

open access: yesHeliyon, 2020
Pregnancy is known to be associated with an increased demand for insulin that is normally compensated by an increased beta cell mass and insulin secretion.
Amarnadh Nalla   +5 more
doaj  

Tuberculosis clinical presentation and treatment outcomes in pregnancy: a prospective cohort study

open access: yesBMC Infectious Diseases, 2020
Background There is limited research to guide TB treatment specifically in pregnant women and few studies have described the presentation of TB in pregnant women.
Brittney J. van de Water   +10 more
doaj   +1 more source

Occupational stress is associated with job performance among pregnant women in Japan: comparison with similar age group of women

open access: yesBMC Pregnancy and Childbirth, 2022
Background Pregnancy results in physical and psychological changes in women; however, pregnant women hesitate to take a break from work even when they feel the need.
Yasuka Nakamura   +7 more
doaj   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

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