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IntroductionWomen with diminished ovarian reserve (DOR) have a lower pregnancy rate and higher cancellation rate compared to those without DOR when seeking assisted reproductive technology. However, which factors are associated with reproductive outcomes
Lu Li +19 more
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Objective: To determine if the application of time-lapse incubation and monitoring can be beneficial to clinical outcomes in assisted reproductive technology.Methods: A total of 600 patients were equally randomized to three groups, namely, conventional ...
Yu-han Guo +19 more
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Genetic testing in Marfan syndrome [PDF]
Genetic testing is aiding rapid diagnosis of Marfan syndrome as a basis for management of eye, heart and skeletal disease. The affected patient's mutation can be used as a basis for prenatal or postnatal diagnosis of offspring.
Aragon-Martin, JA, Child, AH, Sage, K
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Preimplantation genetic testing (PGT) for monogenic disorders and assisted reproductive technology have evolved and progressed in tandem. PGT started with single-cell polymerase chain reaction (PCR) followed by fluorescent in situ hybridisation for a ...
Firuza R Parikh +7 more
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Errors in chromosome segregation during oogenesis and early embryogenesis [PDF]
Errors in chromosome segregation occurring during human oogenesis and early embryogenesis are very common. Meiotic chromosome development during oogenesis is subdivided into three distinct phases.
A Dyban +65 more
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The Relationship Between Serum Delta FSH Level and Ovarian Response in IVF/ICSI Cycles
BackgroundWhen ovarian response to FSH stimulation for IVF/ICSI is unsatisfactory, the FSH dose is often adjusted in the treatment cycles, thereby assuming that hormone status and follicular development were insufficient for optimal stimulation ...
Linli Hu +27 more
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Laser microdissection as a new approach to prefertilization genetic diagnosis [PDF]
The genetic status of oocytes can be determined by polar body (PB) analysis. Following PB extraction, a genetic evaluation is performed. As each PB contains the complementary genetic material of the oocyte, PB analysis reveals information about its ...
Buchholz, Tina +2 more
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Preimplantation Genetic Diagnosis
Preimplantation genetic diagnosis or screening is a very early form of prenatal diagnosis that allows embryos to be tested for genetic disorders before pregnancy has begun. The procedure offers an advantage for couples with genetic disorders whose offspring has an increased risk of a specific genetic condition by helping in the delivery of a healthy ...
Pavelić, Krešimir +1 more
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Birth of a healthy child fathered by a man with Klinefelter`s syndrome after preimplantation genetic testing [PDF]
Introduction. Most men with non-mosaic Klinefelterʼs syndrome (KS; 47, XXY) have azoospermia, and were until recently considered completely infertile. However, it has been confirmed that some non-mosaic patients had spermatozoa in the ejaculate, although
Trninić-Pjević Aleksandra +4 more
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Multicolour interphase cytogenetics: 24 chromosome probes, 6 colours, 4 layers [PDF]
From the late 1980s onwards, the use of DNA probes to visualise sequences on individual chromosomes (fluorescent in-situ hybridisation - FISH) revolutionised the study of cytogenetics.
A.R. Thornhill +61 more
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