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Preimplantation genetic diagnosis
The Lancet, 2004 Preimplantation genetic diagnosis (PGD) was introduced at the beginning of the 1990s as an alternative to prenatal diagnosis, to prevent termination of pregnancy in couples with a high risk for offspring affected by a sex-linked genetic disease. At that time, embryos obtained in vitro were tested to ascertain their sex, and only female embryos were ...
Sermon, Karen +2 more
core +12 more sources
Human Reproduction, 1992 Although healthy babies have been born after preimplantation diagnosis for sex determination, this technique is still in an experimental phase. To date, removal by micromanipulation of one or two blastomeres from an eight-cell embryo seems an acceptable procedure.
Liebaers, Ingeborg +6 more
core +6 more sources
Preimplantation genetic diagnosis
Nature Reviews Genetics, 2002 Preimplantation genetic diagnosis (PGD) is an evolving technique that provides a practical alternative to prenatal diagnosis and termination of pregnancy for couples who are at substantial risk of transmitting a serious genetic disorder to their offspring.
Braude, P +3 more
core +6 more sources
Targeting myotonic dystrophy by preimplantation genetic diagnosis-karyomapping
Taiwanese Journal of Obstetrics & Gynecology, 2019 Objective: To report a case with Myotonic dystrophy type I with successful preimplantation genetic diagnosis-karyomapping. Case report: A 34-year-old female carrier of myotonic dystrophy type I was treated at our clinic with a successful pregnancy after ...
Cheng-Wei Wang +2 more
doaj +2 more sources
Clinics in Perinatology, 2003 Preimplantation genetic diagnosis is a valuable addition to the repertoire of reproductive medicine because it gives individuals with a documented history of a genetic disorder the opportunity to begin a wanted pregnancy with little or no fear that they are transmitting this disorder to their offspring.
Pedersen, Roger A. +3 more
openaire +3 more sources
[Preimplantation genetic diagnosis].
Ugeskrift for laeger, 2018 In Denmark, preimplantation genetic diagnosis (PGD) is offered within the public healthcare to families with a known risk of an inherited disease in a child - as an alternative to prenatal diagnosis. It is a well-established technique with rather well-described perinatal- and neonatal outcomes, being comparable to what is seen following in vitro ...
Ingerslev, Hans Jakob +7 more
openaire +4 more sources
Prenatal and preimplantation diagnosis of hemoglobinopathies [PDF]
International Journal of Laboratory Hematology, 2018 AbstractThe hemoglobinopathies, as a group, are one of the most common serious monogenic diseases in the world. An accepted and widely adopted approach to reduce the number of new cases involves carrier‐screening programs, with the option of prenatal diagnosis (PND) or preimplantation diagnosis (preimplantation genetic testing for monogenic disease ...
C. Vrettou +3 more
openaire +4 more sources
Preimplantation genetic diagnosis associated to Duchenne muscular dystrophy
Einstein (São Paulo), 2017 Duchenne muscular dystrophy is the most common muscle disease found in male children. Currently, there is no effective therapy available for Duchenne muscular dystrophy patients. Therefore, it is essential to make a prenatal diagnosis and provide genetic
Bianca Bianco +3 more
doaj +2 more sources
Preimplantation genetic diagnosis
Zdravniški Vestnik, 2013 Backg round: Preimplantation genetic diagnosis (PGD) is used to analyze embryos before their transfer into uterus. It is suitable for a group of patients who are at a substantial risk of conceiving a pregnancy affected by a known genetic defect.
Karin Writzl
doaj +1 more source
Metabolomics in Prenatal Medicine: A Review
Frontiers in Medicine, 2021 Pregnancy is a complicated and insidious state with various aspects to consider, including the well-being of the mother and child. Developing better non-invasive tests that cover a broader range of disorders with lower false-positive rates is a ...
Giovanni Monni +7 more
doaj +1 more source