Prevalência do uso de diagnóstico genético pré-Implantação na Unidade Clínica de Paramiloidose do Centro Hospitalar do Porto [PDF]
, 2014 Introduction: The Familial Amyloid Polyneuropathy, with the world’s largest focus in Portugal, is recognized by the National Board of Assisted Reproductive Technologies as a serious disease eligible for Preimplantation Genetic Diagnosis.
Alves, E. +3 more
core +2 more sources
Rapid mapping of chromosomal breakpoints: from blood to BAC in 20 days [PDF]
, 2009 Structural chromosome aberrations and associated segmental or chromosomal aneusomies are major causes of reproductive failure in humans. Despite the fact that carriers of reciprocal balanced translocation often have no other clinical symptoms or ...
Baumgartner, Adolf +7 more
core +2 more sources
New perspectives on preimplantation genetic diagnosis and preimplantation genetic screening
Taiwanese Journal of Obstetrics & Gynecology, 2014 Preimplantation genetic diagnosis is a procedure that involves the removal of one or more nuclei from oocytes (a polar body) or embryos (blastomeres or trophectoderm cells) in order to test for problems in genome sequence or chromosomes of the embryo ...
Chun-Kai Chen +3 more
doaj +1 more source
Endometrial thickness and early pregnancy complications after frozen-thawed embryo transfers
Frontiers in Endocrinology, 2023 BackgroundThe relationship between endometrial thickness and pregnancy safety after in vitro fertilization treatment is an important topic that should provoke attention.
Lin Song +11 more
doaj +1 more source
Preimplantation Genetic Diagnosis
AMA Journal of Ethics, 2001 Preimplantation genetic diagnosis raises ethical and moral concerns about using one person as a means to save another, especially as highlighted in recent cases where parents have more children in the hopes of saving a sick child. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.
openaire +5 more sources
Strategy for the creation of clinical grade hESC line banks that HLA‐match a target population
EMBO Molecular Medicine, 2012 Here, we describe a pre‐derivation embryo haplotyping strategy that we developed in order to maximize the efficiency and minimize the costs of establishing banks of clinical grade hESC lines in which human leukocyte antigen (HLA) haplotypes match a ...
Laureen Jacquet +9 more
doaj +1 more source
Targeting myotonic dystrophy by preimplantation genetic diagnosis-karyomapping
Taiwanese Journal of Obstetrics & Gynecology, 2019 Objective: To report a case with Myotonic dystrophy type I with successful preimplantation genetic diagnosis-karyomapping. Case report: A 34-year-old female carrier of myotonic dystrophy type I was treated at our clinic with a successful pregnancy after ...
Cheng-Wei Wang +2 more
doaj +1 more source
Ethics of modifying the mitochondrial genome [PDF]
, 2010 Recent preclinical studies have shown the feasibility of specific variants of nuclear transfer to prevent mitochondrial DNA disorders. Nuclear transfer could be a valuable reproductive option for carriers of mitochondrial mutations.
Bredenoord, A L +3 more
core +3 more sources
Pre-implantation Genetic Diagnosis of Thalassemias
Thai Journal of Obstetrics and Gynaecology, 2018 Beta-Thalassemia major, beta-thalassemia-Hb E disease and Hb Bart’s disease are severe hereditary anemia which are prevalent in Thailand and neighborhood countries.
Wirawit Piyamongkol
doaj +1 more source
A Right to Choose?: Sex Selection in the International Context [PDF]
, 2007 While there is some debate among doctors, ethicists, and the general public about the level of medical necessity that should justify a sex-selection procedure, most accept that sex selection for medical reasons is beyond ethical reproach, and in some ...
Bumgarner, Ashley
core +2 more sources