Results 71 to 80 of about 12,612 (210)

Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss

Equine Veterinary Journal, Volume 58, Issue 4, Page 970-980, July 2026.
Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez, Alejandro de la Fuente, Kazuki Takahashi, Hugo Monteiro, Mauricio Mendes, Stuart Meyers, Pouya Dini   +6 more
wiley   +1 more source

A novel variation in DEPDC5 causing familial focal epilepsy with variable foci

Frontiers in Genetics
BackgroundDisheveled, EGL-10, and pleckstrin (DEP) domain-containing protein 5 (DEPDC5) is a component of GTPase-activating protein (GAP) activity toward the RAG complex 1 (GATOR1) protein, which is an inhibitor of the amino acid-sensing branch of the ...
Yanchi Wang, Yanchi Wang, Yanchi Wang, Yanchi Wang, Wenbin Niu, Wenbin Niu, Wenbin Niu, Wenbin Niu, Hao Shi, Hao Shi, Hao Shi, Hao Shi, Xiao Bao, Xiao Bao, Xiao Bao, Xiao Bao, Yidong Liu, Yidong Liu, Yidong Liu, Yidong Liu, Manman Lu, Manman Lu, Manman Lu, Manman Lu, Yingpu Sun, Yingpu Sun, Yingpu Sun, Yingpu Sun   +27 more
doaj   +1 more source

Preimplantation genetic diagnosis: International standards and the law of the republic of Serbia [PDF]

Zbornik Radova: Pravni Fakultet u Novom Sadu, 2014
The process of biomedical assisted reproduction, in addition to the treatment of infertility, also can be implemented for the purpose of prevention of transmission of serious hereditary disease to offspring. This is possible thanks to the preimplantation
Rajić Nataša
doaj   +1 more source

Attitudes toward prenatal diagnosis and termination of pregnancy in Saudi Arabia [PDF]

, 2004
INTRODUCTION: Advances in molecular biology will soon make it possible to offer parents prenatal testing for a large number of different genetic disorders.
Alsulaiman, Ayman
core  

Regretting mother‐ and fatherhood in Switzerland: Equal parenthood regret but for different reasons

Family Relations, Volume 75, Issue 3, Page 1841-1856, July 2026.
Abstract Objective This article investigates the prevalence of and factors associated with parenthood regret in Switzerland. Background There is increasing evidence that parenthood regrets occur both in mothers and fathers, but little is known about their causes and how they relate to gendered norms and conditions of parenthood.
Larissa Fritsch, Sandra Gilgen
wiley   +1 more source

A thinner endometrium is associated with a greater risk of preterm delivery after fresh cleavage embryo transfer but not after blastocyst transfer: a retrospective cohort study of 11,111 singleton live births

Frontiers in Endocrinology
BackgroundEndometrial thickness (EMT) has been confirmed to be associated with pregnancy outcomes after in vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET), but studies on its relationship with neonatal outcomes are ...
Tian Ye, Tian Ye, Tian Ye, Tian Ye, Huijuan Kong, Huijuan Kong, Huijuan Kong, Huijuan Kong, Zhiqin Bu, Zhiqin Bu, Zhiqin Bu, Zhiqin Bu, Wenqian Fan, Wenqian Fan, Wenqian Fan, Wenqian Fan, Linqing Du, Linqing Du, Linqing Du, Linqing Du, Jing Li, Jing Li, Jing Li, Jing Li, Yihong Guo, Yihong Guo, Yihong Guo, Yihong Guo   +27 more
doaj   +1 more source

Preimplantation diagnosis of genetic diseases

Journal of Postgraduate Medicine, 2010
One of the landmarks in clinical genetics is prenatal diagnosis of genetic disorders. The recent advances in the field have made it possible to diagnose the genetic conditions in the embryos before implantation in a setting of in vitro fertilization.
Adiga, S.K., Kalthur, G., Kumar, P., Girisha, K.M.   +3 more
openaire   +2 more sources

Impact of Rapid Exome Sequencing on Pediatric Patients With Cardiomyopathy and Acute Heart Failure

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1222-1230, June 2026.
ABSTRACT Few studies describe the impact of rapid exome sequencing (ES) on pediatric cardiomyopathy in urgent clinical settings. Here, we retrospectively report the impact of rapid singleton ES in pediatric patients presented with acute heart failure and isolated cardiomyopathy or myocarditis, between 2021 and 2023 at a single tertiary care center.
Tameemi Abdalla Moady, Tova Hershkovitz, Clair Habib, Ori Attias, Amir Hadash, Galit Tal, Asaad Khoury, Josef Ben‐Ari, Danny Eytan, Tamar Paperna, Karin Weiss   +10 more
wiley   +1 more source

Facilitating Genetic Testing for Perinatal Demise: Development of a Multidisciplinary Workflow

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1273-1285, June 2026.
ABSTRACT Genetic contributors to perinatal demise are common but frequently undiagnosed due to clinical and logistical barriers. We aimed to improve access to genetic for intrauterine fetal demise (IUFD), stillbirth, and early neonatal death by developing a multidisciplinary workflow.
Mackenzie Mosera, Samantha Stover, Elise Boos, Molly Casey, Joseph Fanning, Chelsea Fechter, Matthew Grace, L. Dupree Hatch, Michaela Ibach, Carla Jackson, Jiancong Liang, Caitlin Mann, Emily A. Morris, Jessica Turnbull, Marie Williams, Bryce A. Schuler   +15 more
wiley   +1 more source

Investigation of DNA repair in human oocytes and preimplantation embryos

, 2010
DNA repair genes are expressed in mammalian embryos and in human germinal vesicles, however, little is known about DNA repair in human preimplantation embryos.
Jaroudi, S.
core