DNA methylation meets lineage tracing: History, recent progress, and future directions
Quantitative Biology, Volume 14, Issue 1, March 2026.Abstract Lineage tracing techniques have been developed rapidly in the past decades by employing new genetic engineering tools. However, due to their invasive nature, these are difficult to apply to humans. Although endogenous DNA mutations can be used for in vivo lineage tracing in humans, their extremely low mutation rate presents substantial ...
Ruijiang Fu +2 more
wiley +1 more source
Preimplantation genetic testing for aneuploidy (PGT-A) and technology platform: does platform influence euploid call rates and/or subsequent pregnancy outcomes? [PDF]
, 2019 Eleni A. Greenwood +6 more
openalex +1 more source
Effects of Embryo Production Method and Culture Medium on Embryonic Development in Red‐Rumped Agouti
Cell Biology International, Volume 49, Issue 12, Page 1655-1668, December 2025.ABSTRACT Advances in Assisted Reproductive Technologies (ARTs) help overcome reproductive barriers. However, a comprehensive understanding of embryonic development is crucial for their success. In vitro fertilization (IVF) and artificial oocyte activation (AOA) are embryo production methods commonly used.
Lhara Ricarliany Medeiros de Oliveira +5 more
wiley +1 more source
ATRX: From Chromatin Remodeling to Disease
genesis, Volume 63, Issue 6, December 2025.ABSTRACT Chromatin remodeling proteins are evolutionarily conserved factors involved in a wide range of biological processes. In this review, we describe ATRX, a chromatin remodeling protein belonging to the SWI/SNF2 family. Its association with different protein complexes, and its roles in embryonic development, sexual differentiation, as well as ...
Mauro Magaña‐Acosta +1 more
wiley +1 more source
Tea Polyphenols Enhance Embryonic Development and Mitigate DMSO‐Induced Toxicity in Drosophila
eFood, Volume 6, Issue 6, December 2025.This study found that tea polyphenols, especially from oolong and black tea, promote embryonic development and reduce oxidative stress in fruit flies. While DMSO is toxic at higher doses, tea polyphenols, particularly catechin and EGCG, mitigate its harmful effects, enhancing vitality, development, and stress resistance of fruit flies.
Quanyong Wu +5 more
wiley +1 more source
Research progress and challenges of preimplantation genetic testing for polygenic diseases
, 2023 Xiaojing Wu +3 more
openalex +1 more source
O-287 Preimplantation genetic testing for monogenic disease (PGT-M) where results are only based upon analysis of linked polymorphisms/haplotypes risks serious diagnostic errors [PDF]
, 2023 Ayman Haj Ali +5 more
openalex +1 more source
Intralitter Variability Influences the Developmental Impact of Valproic Acid Exposure in CD‐1 Mice
Journal of Applied Toxicology, Volume 45, Issue 12, Page 2624-2640, December 2025.ABSTRACT Valproic acid (VPA) is an antiepileptic and mood‐stabilizing drug that causes teratogenic effects, including neural tube defects (NTDs), when taken during pregnancy. Although animal models are widely used to study VPA teratogenicity, most rely on litter means, which overlook variability within the litter.
Lauren T. L. Brown +3 more
wiley +1 more source
Journal of Genetic Counseling, Volume 34, Issue 6, December 2025.Abstract Duchenne muscular dystrophy (DMD) is an X‐linked genetic condition characterized by progressive muscle degeneration. Recently, several genotype‐specific treatment options for DMD have become available. Prenatal genetic counselors may encounter at‐risk patients for DMD, through a variety of indications.
Shawna L. Jurlina +3 more
wiley +1 more source
Medical-ethical recommendations: preimplantation genetic testing PGT
Swiss Medical Weekly, 2020 Swiss Medical Weekly
doaj +1 more source