Results 121 to 130 of about 24,363 (274)

Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes

Andrology, Volume 14, Issue 2, Page 528-544, February 2026.
ABSTRACT Background Epidemiological studies have reported an association between advanced paternal age at conception and an increased risk of neurodevelopmental disorders in offspring, such as autism spectrum disorder. Evidence suggests that DNA methylation alterations in spermatozoa of older men may be transmitted to the feto‐placental unit and ...
Julia Barnwell, Sophia Rahimi, Sherri Lee Jones, Donovan Chan, Josée Martel, Sara Abdessamie, Catherine M. Herba, Jean R. Séguin, William D. Fraser, Celia M. T. Greenwood, Tuong‐Vi Nguyen, Tina C. Montreuil, Jacquetta Trasler   +12 more
wiley   +1 more source

INFLAMMATION IS ASSOCIATED WITH NUMBER OF EGGS AND EUPLOID EMBRYOS BUT NOT EUPLOIDY RATE IN PREIMPLANTATION GENETIC TESTING FOR ANEUPLOIDY (PGT-A) [PDF]

, 2023
Emily E. Auran, David H. McCulloh, Lucy Lu, J. Grifo   +3 more
openalex   +1 more source

Exploring Repro‐Timing Harm and Benefit

Bioethics, Volume 40, Issue 2, Page 201-210, February 2026.
ABSTRACT It is plausible that time of birth affects one's prospects for wellbeing. Being born during a war or recession might have a negative impact on early life and lifetime wellbeing. In natural reproduction, delaying conception does not result in the same child being born later, but rather a different child altogether; therefore, prospective ...
Davide Battisti, Gary David O'Brien
wiley   +1 more source

Haplotyping by linked-read sequencing (HLRS) of the genetic disease carriers for preimplantation genetic testing without a proband or relatives [PDF]

, 2020
Li Q, Yan Mao, Shaoying Li, Hongzi Du, Wenzhi He, Jianchun He, Lingyin Kong, Jun Zhang, Bo Liang, Jianqiao Liu   +9 more
openalex   +1 more source

The impact of an interventional counselling procedure in families with a BRCA1/2 gene mutation : efficacy and safety [PDF]

, 2016
Background: Predictive genetic testing has high impact on cancer prevention for BRCA carriers and passing this information in BRCA families is important.
Bonduelle, Maryse, De Greve, Jacques, Delesie, Liesbeth, Deschepper, Ellen, Pauwels, Ingrid, Sermijn, Erica, Teugels, Erik   +6 more
core   +2 more sources

Biochemical Testing Promotes Interpretation of Variants of Uncertain Significance in Prenatal Genetic Disease Testing in Four Organic Acidurias

Clinical Genetics, Volume 109, Issue 2, Page 211-217, February 2026.
This review demonstrates how amniotic fluid biochemical testing provides critical phenotypic evidence (ACMG PP4) for reclassifying variants of uncertain significance (VUS) in prenatal organic acidurias. Integrating metabolite analysis with genetic testing enhances diagnostic accuracy and enables informed clinical decisions for affected families ...
Kaili Yin, Qingwei Qi
wiley   +1 more source

PREIMPLANTATION GENETIC TESTING: 30 years of preimplantation genetic testing [PDF]

Reproduction, 2020
openaire   +1 more source

Sci‐Fi Parenthood and the End of Love

Journal of Social Philosophy, EarlyView.
Daniela Cutas
wiley   +1 more source

Genetic Insights and Lifelong Management of Aldosterone Synthase Deficiency: A Case of Hyperreninemic Hypoaldosteronism

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Aldosterone synthase deficiency is a rare cause of neonatal salt‐wasting and failure to thrive. Routine newborn electrolyte screening after 5 days of life is vital for early detection and prevention of life‐threatening crises. Genetic confirmation enables targeted fludrocortisone therapy, ensuring favorable growth and developmental outcomes.
Mian Muhammad Hassan Ahmed, Rehmana Waris, Samra Batool, Rahmat Gul Omarzai, Abdur Rehman   +4 more
wiley   +1 more source

Outcome of Couples with Reciprocal Translocation Carrier Undergoing the First Preimplantation Genetic Testing Cycles

Reproductive and Developmental Medicine, 2018
Background: Reciprocal translocation (RCP) causes male infertility and female recurrent pregnancy loss. Male and female carriers have different responses to meiotic disturbances. Gender difference in outcomes of the RCP couples undergoing preimplantation
Cai-Xia Lei, Shuo Zhang, Hai-Yan Sun, Sai-Juan Zhu, Jing Zhou, Jing Fu, Yi-Juan Sun, Jun-Ping Wu, Yue-Ping Zhang, Xiao-Xi Sun   +9 more
doaj   +1 more source