Results 81 to 90 of about 304,421 (272)
The Subjectivity of Effective History and the Suppressed Husserlian Elements in Gadamer’s Philosophical Hermeneutics [PDF]
This essay makes two claims. The first, exegetical, point shows that there are Husserlian elements in Gadamer’s hermeneutics that are usually overlooked.
Luft, Sebastian
core +1 more source
A Radical Revolution in Thought: Frederick Douglass on the Slave’s Perspective on Republican Freedom [PDF]
While the image of the slave as the antithesis of the freeman is central to republican freedom, it is striking to note that slaves themselves have not contributed to how this condition is understood.
Coffee, Alan M. S. J.
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
RESUMEN: Se analiza con elementos concretos cómo en Cuba a partir del primero de enero de 1959 la situación de la sociedad cubana cambió profundamente y en particular la de la mujer.
Maribel Almaguer Rondón
doaj
The article gives a historical overview and the state of the art concerning childhood stuttering. It deals with the well-established and recommended methods of treating stuttering and of advising parents.
Patricia Sandrieser
doaj
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
innovation, employee control, efficiency, resistance to social change, dirty work
This article presents the theoretical framework and the results of a research conducted in a brewery with respect to the concept of gender discrimination. The main objective of the research is to identify gender inequalities and
Ada Ioana Dobrescu
doaj +1 more source

