Results 91 to 100 of about 2,332,453 (308)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Alexandrov geometry: preliminary version no. 1

open access: yes, 2019
This is a preliminary version of our book. It goes up to the definition of dimension, which is about 30% of the material we plan to include. If you use it as a reference, do not forget to include the version number since the numbering will be changed ...
Alexander, Stephanie   +2 more
core  

A stress free model for residual stress assessment using thermoelastic stress analysis [PDF]

open access: yes, 2014
Thermoelastic Stress Analysis (TSA) has been proposed as a method of obtaining residual stresses. The results of a preliminary study demonstrated that when Al-2024 plate containing holes that were plastically deformed by cold expansion process to 2% and ...
Achintha, Mithila   +3 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Offshore rectenna feasbility [PDF]

open access: yes, 1980
A preliminary study of the feasibility and cost of an offshore rectenna to serve the upper metropolitan east coast was performed. A candidate site at which to build a 5 GW rectenna was selected on the basis of proximity to load centers, avoidance of ...
Freeman, J. W., Glaser, P., Hervey, D.
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Development of a pin-less reference head frame: An experimental setup and preliminary experiences

open access: yesInterdisciplinary Neurosurgery, 2018
Objectives: Advantages of image guidance in neurosurgical procedures are undisputed. Although some approaches of flexible technologies already exist, today's gold standard for neuronavigation is the pin-assisted head clamp fixation. A reference tool that
A. Carolus   +4 more
doaj   +1 more source

Reliability and preliminary reference values for the Total Faulty Breathing Scale (TFBS): A cross-sectional study. [PDF]

open access: yesHealth Sci Rep, 2022
Mohan V   +6 more
europepmc   +1 more source

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