Results 71 to 80 of about 594,207 (265)
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Folia MorphologicaBACKGROUND: Accurate characterization of fetal thoracic development is essential for improving prenatal assessment and early detection of structural abnormalities. The aim of this study was to evaluate the morphometric and proportional characteristics of
Vusale Dadashova +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Stepwise fusion algorithm with dual correction for multi-sensor navigation
International Journal of Advanced Robotic Systems, 2018 In high-altitude, long-endurance unmanned aerial vehicles, a celestial attitude determination system is used to enhance the inertial navigation system (INS)/global positioning system (GPS) to achieve the required attitude performance.
Rong Wang +3 more
doaj +1 more source
Test-Retest Reliability of the Generalized Pain Questionnaire in Patients with Rheumatoid Arthritis and Preliminary Reference Values for Non-Clinical and Several Clinical Samples. [PDF]
J Pain Res, 2023 Jansen N +3 more
europepmc +1 more source
The Reference for a Preliminary Ruling. CJEU Recommendations [PDF]
Logos Universality Mentality Education Novelty: Law, 2017 The reference for a preliminary ruling is the most useful legal instrument available to the national courts in order to obtain an authentic interpretation of a European Union legislative act or to check the validity of a Union act. The article examines the Court of Justice's recommendations on the reference for a preliminary ruling, recommendations ...
openaire +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Reliability and preliminary reference values for the Total Faulty Breathing Scale (TFBS): A cross-sectional study. [PDF]
Health Sci Rep, 2022 Mohan V +6 more
europepmc +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source