Results 51 to 60 of about 594,207 (265)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Understanding Academic Patrons’ Data Needs through Virtual Reference Transcripts: Preliminary Findings from New York University Libraries

IASSIST Quarterly, 2016
Understanding Academic Patrons’ Data Needs through Virtual Reference Transcripts: Preliminary Findings from New York University ...
Margaret Smith, Jill Conte, Samantha Guss   +2 more
doaj   +1 more source

Preliminary Reference and the Hungarian Constitutional Court: A Context of Non-Reference [PDF]

German Law Journal, 2015
Jiri Zemanek, Professor at Charles University, Prague, asks what conclusions may be drawn from the current state of acceptance of the European Union (EU) law doctrine by the constitutional courts of the new Member States for their performance in the agenda of preliminary rulings. What can they learn from the experience of the old Member States?
openaire   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Access to Written Submissions in Preliminary Reference Proceedings: An Evaluation of the CJEU Statute Reform and its Contribution to Open Justice

European Papers
(Series Information) European Papers - A Journal on Law and Integration, 2025 10(2), 357-389 | Article | (Table of Contents) 1. Introduction. – 2. Open justice and human rights: ensuring transparency and accountability through public access. – 2.1.
Ilaria Fevola, Stefano Montaldo
doaj   +1 more source

Protecting the Jewel in the Crown: The Ognyanov Case and the Preliminary Reference Procedure

European Papers, 2017
(Series Information) European Papers - A Journal on Law and Integration, 2017 2(1), 393-401 | European Forum Insight of 11 April 2017 | (Table of Contents) I. The Ognyanov case. - I.1. The facts and the preliminary reference. - I.2.
Francisco Pereira Coutinho
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Preliminary Study on Reference Interval of Serum Pepsinogen in Healthy Subjects

Patient Preference and Adherence, 2021
Liang Zhang, Ye Niu, Yin-Jiang Lv, Li-Feng Wu, Qi-Lei Hu, Rong Huang, Ru-Jin Xu Department of Clinical Laboratory, First People’s Hospital of Linping District, Hangzhou, Zhejiang, 311100, People’s Republic of ChinaCorrespondence: Ru-Jin XuDepartment of ...
Zhang L, Niu Y, Lv YJ, Wu LF, Hu QL, Huang R, Xu RJ   +6 more
doaj  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source