Results 41 to 50 of about 2,350,866 (345)

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

Test–Retest Reliability of the Generalized Pain Questionnaire in Patients with Rheumatoid Arthritis and Preliminary Reference Values for Non-Clinical and Several Clinical Samples

open access: yesJournal of Pain Research, 2023
Niels Jansen,1 Peter M ten Klooster,2 Harald E Vonkeman,3 Jan R Buitenweg1 1Biomedical Signals and Systems, University of Twente, Enschede, the Netherlands; 2Psychology, Health & Technology, University of Twente, Enschede, the Netherlands; 3Department of
Jansen N   +3 more
doaj  

Global-Scale Numerical Modeling of Seismic Wave Propagation Using PREM and Unstructured Triangular Meshing: Insights into the Layered Structure of Earth [PDF]

open access: yesمجله فیزیک زمین و فضا
The Preliminary Reference Earth Model (PREM) provides a robust framework for understanding seismic wave propagation through Earth’s layered interior. This study employs numerical forward modeling to simulate P-wave and S-wave ray paths, travel times, and
Amir Yazdanpanah, Maysam Abedi
doaj   +1 more source

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich   +5 more
wiley   +1 more source

Los derechos sociales en la Constitución y el juez de Luxemburgo

open access: yesRevista Vasca de Administración Pública, 2017
The constitutional recognition of social rights raises the problem of their legal effectiveness. In most cases, their guarantee depends on the law that specifies their content based on generic constitutional principles.
Marc Carrillo López
doaj   +1 more source

Environmental assessment overview [PDF]

open access: yes, 1980
The assessment program has as its objectives: to identify the environmental issues associated with the SPS Reference System; to prepare a preliminary assessment based on existing data; to suggest mitigating strategies and provide environmental data and ...
Valentino, A. R.
core   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

MeerKAT time and frequency reference optical network: Preliminary design analysis

open access: yesSouth African Journal of Science, 2017
The MeerKAT telescope is a precursor to the Square Kilometre Array, which will rely on optical fibres to link the telescope receivers to a central processor point. The main aspects to consider for the fibre transport are astronomical data transmission as
Enoch K. Rotich Kipnoo   +6 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

La chiusura del dialogo “giudice a giudice” come extrema ratio nella sentenza L.G. c Krajowa Rada Sadownictwa

open access: yesEuropean Papers
(Series Information) European Papers - A Journal on Law and Integration, 2024 9(1), 275-286 | European Forum Insight of 15 July 2024 | (Table of Contents) I. Introduzione. - II.
Miriana Lanotte
doaj   +1 more source

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