Results 91 to 100 of about 2,227,232 (332)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Review articles as windows into Knowledge accumulation: the case of AI research

open access: yesInformation Research: An International Electronic Journal
Introduction. Review articles are essential in evolving scholarly information systems but have been underexplored in scientometrics. This paper aims to expand scientometric research on review articles, focusing on their role in understanding knowledge ...
Siyuan Peng   +4 more
doaj   +1 more source

Application of palynological techniques for correlation of coal seams in the Lower Lignite Creek area, Nenana Coal Field [PDF]

open access: yes, 1980
This study concerns spores and pollen in the coals of the lower Lignite Creek area in the Nenana Coal Field, which is operated by Usibelli Mining Company.
McFarlane, R., Sanders, R., and Rao, P.D.
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

THE CLAUSES OF EXCEPTION IN “DOMESTIC LAW” AND IN HAGUE CONVENTIONS

open access: yesRevista Eletrônica de Direito Processual, 2019
The present work is proposed after a necessary preliminary examination on the terminology and classification level to analyze the clauses (in comparative mode) in question under EU legislation and jurisprudence at a conventional level.
Dimitris Liakopoulos
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Human acclimation and acclimatization to heat: A compendium of research, 1968-1978 [PDF]

open access: yes
s and annotations of the majority of scientific works that elucidate the mechanisms of short-term acclimation to heat in men and women are presented. The compendium includes material from 1968 through 1977.
Fox, S. C.   +3 more
core   +1 more source

Disproportionate Detention of Minorities: A Case Study of One State's Compliance with the Mandates of the Juvenile Justice and Delinquency Prevention Act [PDF]

open access: yes, 1996
Pursuant to Section 223(a)(23) of the Juvenile Justice and Delinquency Prevention Act, states must examine whether minority youth are disproportionately detained in relation to their proportion in the general population.
Curtis, Richard W., Schafer, N. E.
core  

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