Results 81 to 90 of about 2,227,232 (332)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
EDIS, 2008 HS-1123, a 4-page illustrated fact sheet by Robert C. Hochmuth, Eric H. Simonne, Lei Lani L. Davis, and Wanda L. Laughlin, describes the use of quick test in hydroponic greenhouse herb production.
Robert C. Hochmuth +3 more
doaj +1 more source
(Dimensional) twisted reduction in large N gauge theories
, 2015 We show that the spontaneous breaking of center symmetry can be avoided on a $L^2\times 1^2$ lattice with the appropriate choice of twisted boundary conditions.
Keegan, Liam, Ramos, Alberto
core +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
External field influence on semiflexible macromolecules: geometric coupling
, 2011 We suggested a geometric approach to address the external field influence on the DNA molecules, described by the WLC model via geometric coupling. It consists in the introduction of the effective metrics depending on the potential of the external field ...
Bellucci, Stefano +2 more
core +1 more source
Croatian Yearbook of European Law & Policy, 2020 This paper explores factors that either motivate or constrain national judges’ participation in the preliminary ruling procedure. By incorporating insights and evidence from American judicial politics literature and drawing from three models of judicial decision making: the attitudinal model, the team model, and the resource management model, it places
openaire +6 more sources
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Jurnal Pendidikan Sains Universitas Muhammadiyah Semarang, 2020 This study aims to find out: (i) video-based vibration learning model from http://youtube.com to improve concept understanding; (ii) the feasibility of the learning model; and (iii) strengths and weaknesses of the learning model.
I Gede Rasagama
doaj +1 more source
, 2013 We perform the first general relativistic force-free simulations of neutron star (NS) magnetospheres in orbit about spinning and non-spinning black holes.
Etienne, Zachariah B. +2 more
core +1 more source