Results 101 to 110 of about 1,240 (130)
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‘Exaggerated adrenarche’ in children presenting with premature adrenarche
Clinical Endocrinology, 1995SummaryOBJECTIVE Previous reports of endocrinological profiles in children presenting with premature adrenarche have not shown consistent abnormalities. We therefore aimed to review the clinical and biochemical aspects of a large number of patients presenting with premature adrenarche without virilization and determine the relation between clinical and
S, Likitmaskul +6 more
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Clinical Presentation of Children with Premature Adrenarche
Clinical Pediatrics, 2011Objectives. To describe the phenotype of premature adrenarche (PA) patients, elucidate historical and physical correlates, and distinguish PA from late-onset congenital adrenal hyperplasia (LOCAH). Study design. Retrospective chart review of 122 patients (91 female and 31 male) with PA and 11 with LOCAH. Results.
Julia, von Oettingen +3 more
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Vitamin D status and premature adrenarche
Pediatrics International, 2018AbstractBackgroundVitamin D, an important factor in calcium‐phosphate homeostasis, has recently been suggested to play an important role in the pathogenesis of numerous chronic conditions such as hyperandrogenism. The aim of this study was to investigate the relationship between vitamin D status and premature adrenarche (PA).MethodsA total of 71 girls ...
Onur Akın +8 more
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Lipoprotein(a) levels in girls with premature adrenarche
Journal of Paediatrics and Child Health, 2007Aim: Elevated lipoprotein(a) (Lp(a)) level is a risk factor for cardiovasculary disease (CVD). Women with polycystic ovary syndrome (PCOS) have higher Lp(a) and risk for CVD than controls. The girls with premature adrenarche (PA) were shown to share similar hormonal/metabolic properties with PCOS.
YORDAM, NURŞEN, Andiran, Nesibe
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Hidradenitis suppurativa as a presenting feature of premature adrenarche
British Journal of Dermatology, 1993We report a girl with premature adrenarche, in whom the presenting feature was hidradenitis suppurativa. This association lends support to the view that hidradenitis suppurativa is an androgen-dependent disorder.
Lewis, F, Messenger, AG, Wales, Jkh
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Premature adrenarche: Etiology, clinical findings, and consequences
The Journal of Steroid Biochemistry and Molecular Biology, 2015Adrenarche means the morphological and functional change of the adrenal cortex leading to increasing production of adrenal androgen precursors (AAPs) in mid childhood, typically at around 5-8 years of age in humans. The AAPs dehydroepiandrosterone (DHEA) and its sulfate conjugate (DHEAS) are the best serum markers of adrenal androgen (AA) secretion and
Raimo, Voutilainen +1 more
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Early puberty in girls: The case of premature adrenarche
Women's Health Issues, 2004In this article we examine the issue of early puberty in girls. First, a brief overview of normal pubertal development is provided, including the two endocrine components of puberty: gonadarche and adrenarche. Second, we critically discuss the controversy regarding whether puberty truly is occurring earlier in girls.
Lorah D, Dorn, Deborah, Rotenstein
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The molecular basis of premature adrenarche: an hypothesis
Acta Paediatrica, 1999Adrenarche is characterized by a prepubertal rise in adrenal secretion of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS) that is independent of the gonads or gonadotropins. Adrenopause is the corresponding diminution in DHEA and DHEAS concentrations in later life.
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Changes in carotid artery sonogram in premature adrenarche
Journal of Pediatric Endocrinology and Metabolism, 2012Premature adrenarche (PA), the appearance of pubic hair before the age of 8 years in girls and before 9 years in boys, may predict future morbidity, such as metabolic syndrome (MS).The purpose of this study is to assess carotid artery ultrasound changes in children with PA.PA children were matched with a group of prepubertal controls without PA ...
Revi P, Mathew +4 more
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Genetic variation of FTO and TCF7L2 in premature adrenarche
Metabolism, 2009Premature adrenarche (PA) has been associated with increased body mass index. Our aim was to determine whether the obesity-associated variant at fat mass and obesity gene (FTO) is more frequent in PA subjects. Furthermore, we hypothesized that altered Wnt signaling due to genetic variants at transcription factor 7-like 2 (TCF7L2) could play a role in ...
Saila, Lappalainen +4 more
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