Results 31 to 40 of about 1,240 (130)

Puberty in girls with Prader-Willi syndrome: cohort evaluation and clinical recommendations in a Latin American tertiary center

Frontiers in Endocrinology
IntroductionPrader-Willi syndrome (PWS) is a genetic disorder characterized by hypothalamic-pituitary deficiencies including hypogonadism. In girls with PWS, hypogonadism can present early in childhood, leading to genital hypoplasia, delayed puberty ...
Caroline Gouveia Buff Passone, Luciana Felipe Ferrer Aragão, Ruth Rocha Franco, Junia Ellen Simioni Leite, Michelle Antonella Benitez Gonzalez, Priscila Schuindt de Albuquerque Schil, Marina Ybarra, Durval Damiani, Gerthe Femke Kerkhof, Renan Magalhães Montenegro Junior, Clovis Artur Silva   +10 more
doaj   +1 more source

Review of the Literature on Current Changes in the Timing of Pubertal Development and the Incomplete Forms of Early Puberty

Frontiers in Pediatrics, 2019
Puberty is a sensitive period of life characterized by the appearance of secondary sex characteristics which leads to a complete sexual maturation. It physiologically starts between the age of 8 and 13 years in girls and 9 and 14 years in boys.
Giovanni Farello, Carla Altieri, Maristella Cutini, Gabriella Pozzobon, Alberto Verrotti   +4 more
doaj   +1 more source

The Androstenedione Roche Elecsys immunoassay has superior comparability to the LC-MS/MS assay than the Siemens Immulite immunoassay

Practical Laboratory Medicine, 2022
Androstenedione (ASD) is a biomarker used in the diagnostic workup of hyperandrogenism, congenital adrenal hyperplasia, premature adrenarche, and polycystic ovary syndrome (PCOS).
Ruhan Wei, Kathleen Bowers, Grace M. Kroner, Drew Payto, Jessica M. Colón-Franco   +4 more
doaj   +1 more source

Differences in Endocrine Parameters and Psychopathology in Girls with Premature Adrenarche versus On-time Adrenarche [PDF]

Journal of Pediatric Endocrinology and Metabolism, 2008
Girls with premature adrenarche (PA) are at risk for multiple problems related to exaggerated androgen synthesis. Whether PA carries a risk of psychopathology remains unknown. This study examined group differences in: (a) anthropometric and endocrine parameters, and (b) mood and behavior problems, in 6-8 year-old girls with PA (n = 40) compared to on ...
Lorah D, Dorn, Susan R, Rose, Deborah, Rotenstein, Elizabeth J, Susman, Bin, Huang, Tammy L, Loucks, Sarah L, Berga   +6 more
openaire   +2 more sources

Precocious Puberty and Benign Variants in Female Children: Etiology, Diagnostic Challenges, and Clinical Management

Endocrines
Precocious puberty, defined as the onset of secondary sexual characteristics before age 8 in girls, presents a diagnostic challenge in distinguishing between normal variants and pathological conditions requiring intervention.
Roberto Paparella, Arianna Bei, Lorenzo Brilli, Vittorio Maglione, Francesca Tarani, Marcello Niceta, Ida Pucarelli, Luigi Tarani   +7 more
doaj   +1 more source

Blood Erythrocyte and Hemoglobin Concentrations in Premature Adrenarche [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2013
Premature adrenarche (PA) is characterized by an earlier than normal increase in adrenocortical androgen production, and it is associated with increased serum IGF-I concentrations. Both the GH-IGF system and androgens, particularly testosterone, are known to enhance erythropoiesis.Our objective was to test the hypothesis that blood erythrocyte count ...
Jääskeläinen Jarmo, Voutilainen Raimo, Utriainen Sonja Anna-Pauliina   +2 more
openaire   +2 more sources

Androgen producing oncocytic adrenocortical tumor in a 3.7-year-old female

Endocrinology, Diabetes & Metabolism Case Reports
We report a 3.7-year-old female who presented with clinical features of premature adrenarche. Workup revealed significantly elevated androgen levels and advanced bone maturation, prompting abdominal imaging that identified a 6.0 cm adrenal mass.
Kelli D Mans, Ghada A Elmahmudi, Jiri B Bedrnicek, Monina S Cabrera   +3 more
doaj   +1 more source

Circulating TNF-alpha and IL-6 concentrations and TNF-alpha -308 G>A polymorphism in children with premature adrenarche

Frontiers in Endocrinology, 2010
Premature adrenarche (PA), the early rise in adrenal androgen production leading to prepubertal signs of androgen action, has been connected with adverse metabolic features.
Pauliina eUtriainen, Jarmo eJääskeläinen, Oskari eGröhn, Johanna eKuusisto, Kari ePulkki, Raimo eVoutilainen   +5 more
doaj   +1 more source

The aetiology of extreme tall stature in a screened Finnish paediatric population

EClinicalMedicine, 2021
: Background: Extremely tall children (defined as height SDS (HSDS) ≥+3) are frequently referred to specialized healthcare for diagnostic work-up. However, no systematic studies focusing on such children currently exist.
Juho Kärkinen, MD, Eero Sorakunnas, BM, Päivi J. Miettinen, MD, Taneli Raivio, MD, Matti Hero, MD   +4 more
doaj   +1 more source

Is basal serum 17-OH progesterone a reliable parameter to predict nonclassical congenital adrenal hyperplasia in premature adrenarche?

The Turkish Journal of Pediatrics, 2011
To determine the critical features for the diagnosis of nonclassical 21 hydroxylase deficiency (NC210HD) without performing adrenocorticotropic hormone (ACTH) test, we studied 186 cases with premature adrenarche.
E Nazli Gönç, Z Alev Ozön, Ayfer Alikaşifoğlu, Ozlem Engiz, Burcu Bulum, Nurgün Kandemir   +5 more
doaj