Metabolic and hormonal assessment of adolescent and young adult women with prior premature adrenarche [PDF]
Clinics, 2019 OBJECTIVE: Follow-up studies of girls with premature adrenarche have reported the development of polycystic ovary syndrome, insulin resistance, and dyslipidemia and a propensity to cardiovascular disease. The aim of this study was to analyze the presence
Flávia Alves Ribeiro +5 more
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Long-Term Follow-Up and Risk of PCOS in Indiana Girls with a History of Premature Adrenarche—A Single Center Experience [PDF]
ChildrenBackground/Objectives: The aim of this study was to investigate rates of self-reported Polycystic Ovary Syndrome (PCOS), metabolic abnormalities and age of menarche in girls with a history of Premature Adrenarche (PA) and the association of baseline ...
Rita Saroufim +2 more
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Interpretation of androgen and anti-Mullerian hormone profiles in a Hispanic cohort of 5- to 8-year-old girls with premature adrenarche [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2018 Purpose Premature adrenarche (PA) often leads to polycystic ovary syndrome (PCOS). Higher anti-mullerian hormone (AMH) levels are reported in PCOS. We studied the androgen profile and AMH profiles in Hispanic girls with PA (aged 5–8 years) and age and ...
Preneet Cheema Brar +5 more
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Neuropsychological functioning in girls with premature adrenarche. [PDF]
J Int Neuropsychol Soc, 2012 AbstractContemporary research indicates that brain development occurs during childhood and into early adulthood, particularly in certain regions. A critical question is whether premature or atypical hormone exposures impact brain development (e.g., structure) or function (e.g., neuropsychological functioning).
Tissot A +9 more
europepmc +4 more sources
Girls with a History of Premature Adrenarche Have Advanced Growth and Pubertal Development at the Age of 12 Years [PDF]
Frontiers in Endocrinology, 2017 BackgroundPremature adrenarche (PA) has been linked to early thelarche and menarche, but longitudinal data on growth and pubertal development after PA are insufficient.MethodsGrowth and pubertal development of mostly full-term and appropriate for ...
Jani Liimatta +3 more
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Trajectories of Growth and Serum DHEAS and IGF-1 Concentrations in Girls With a History of Premature Adrenarche: Attenuation of the Phenotype by Adulthood [PDF]
Frontiers in Endocrinology, 2018 Background: It has been speculated that premature adrenarche (PA) could lead to unfavorable outcome, including shorter adult stature, but longitudinal follow-up data are insufficient.Methods: This prospective case-control study included 30 PA and 42 ...
Jani Liimatta +3 more
doaj +2 more sources
Association between glucolipid metabolic indicators and the risk of suspected precocious puberty in children living with obesity: a retrospective cohort study [PDF]
Frontiers in PediatricsObjectiveTo investigate the association between glucolipid metabolic indicators and suspected precocious puberty (PP) in children living with obesity.MethodsThis retrospective observational study initially included 100 children with obesity (BMI ≥95th ...
Tingting Hao, Yifan Li, Qingmei Zhang
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Frontiers in Endocrinology, 2022 ContextWiedemann-Steiner Syndrome (WSS) is a genetic disorder associated with an array of clinical phenotypes, including advanced bone age and short stature.
Katherine Buchanan +4 more
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Pediatric Annals, 2018 Adrenarche is when a child's adrenal cortex starts to secrete adrenal androgen precursors. Dehydroepiandrosterone (DHEA) is the most abundant product of the adrenal cortex, and is a weak androgen agonist thought to be responsible for the clinical signs of pubarche by conversion to more potent androgens, testosterone, and ...
Laura, Novello, Phyllis W, Speiser
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Familial Hyperinsulinism due to HNF4A Deficiency and Benign Premature Adrenarche: A Case Report
International Journal of Medical Students, 2021 Background: Familial Hyperinsulinism due to HNF4A deficiency (FHI-HNF4A) is a form of diazoxide-sensitive, diffuse hyperinsulinism, characterized by transient or persistent hyperinsulinemic hypoglycemia, and a propensity to develop Maturity-Onset ...
Edward Compton +2 more
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