The Relationship Between Premature Adrenarche and Platelet Aggregation [PDF]
JCRPE, 2023 INTRODUCTION: Premature adrenarche (PA) has been associated with an increase in adrenal androgens, and the hyperandrogenic hormonal environment is known to lead to increased platelet (PLT) aggregation.
Ahmet Bolat +4 more
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Normal and Premature Adrenarche. [PDF]
Endocr Rev, 2021 AbstractAdrenarche is the maturational increase in adrenal androgen production that normally begins in early childhood. It results from changes in the secretory response to adrenocorticotropin (ACTH) that are best indexed by dehydroepiandrosterone sulfate (DHEAS) rise.
Rosenfield RL.
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Differential methylation pattern in pubertal girls associated with biochemical premature adrenarche [PDF]
Epigenetics, 2023 Biochemical premature adrenarche is defined by elevated serum DHEAS [≥40 μg/dL] before age 8 y in girls. This condition is receiving more attention due to its association with obesity, hyperinsulinemia, dyslipidemia, and polycystic ovary syndrome ...
Diana Ponce +9 more
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High frequency of autoimmune thyroiditis in euthyroid girls with premature adrenarche [PDF]
Frontiers in Pediatrics, 2023 ObjectiveThe purpose of this study was to investigate the frequency of autoimmune thyroiditis (AT) among euthyroid prepubertal girls presenting with premature adrenarche (PA).
Eleni Magdalini Kyritsi +8 more
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Measurement of 11-Oxo-androgens, A Novel Biomarker, in Females with Clinical Signs of Premature Adrenarche [PDF]
JCRPEObjective: Endocrine findings in premature adrenarche have been characterized by elevated dehydroepiandrosterone (DHEA) DHEA-sulfate (DHEA-S) levels in the past. Methods: We reviewed female patients, aged 4 to 8 years, with premature adrenarche who were
Liana Gabriel +5 more
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Psychiatric and psychosocial characteristics of children with premature adrenarche: a prospective study [PDF]
BMC PediatricsAim Although psychiatric disorders such as depression and anxiety have been reported to be more common in children with precocious puberty, the psychosocial characteristics of puberty variants remain unclear.
Gülçin Arslan +6 more
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Premature Adrenarche in Children with Prader-Willi Syndrome Treated with Recombinant Human Growth Hormone Seems to Not Influence the Course of Central Puberty and the Efficacy and Safety of the Therapy [PDF]
Life, 2020 Puberty in children with Prader-Willi syndrome (PWS) is usually delayed and/or incomplete but in some patients premature/early adrenarche is observed. We assessed the premature adrenarche (PA) in PWS patients during the recombinant human growth hormone ...
Agnieszka Lecka-Ambroziak +4 more
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Clinical Characteristics and Thyroid Findings in Children with Isolated Premature Adrenarche [PDF]
ChildrenObjectives: Premature adrenarche (PA) is associated with accelerated adrenal maturation, but data regarding thyroid characteristics in children with isolated PA are limited.
Sibel Aka +3 more
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Adult Height in Girls With Idiopathic Premature Adrenarche: A Cohort Study and Design of a Predictive Model [PDF]
Frontiers in Endocrinology, 2022 IntroductionIdiopathic premature adrenarche (IPA) is considered a normal variant of puberty, presenting more commonly in female patients. There are concerns as to whether IPA alters the final height of these girls. Our main objectives were to (a) compare
Francisco Javier Mejorado-Molano +6 more
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Association of obesity and adrenal androgen levels with bone age progression in boys with premature adrenarche [PDF]
Annals of Pediatric Endocrinology & MetabolismPurpose Both premature adrenarche (PA) and obesity are closely linked to increases in bone age (BA). However, the mechanisms underlying these associations are unclear as research data, particularly in boys, are lacking.
Kyeongmi Lee +3 more
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