cGAS-STING are responsible for premature aging of telomerase-deficient zebrafish. [PDF]
Şerifoğlu N +8 more
europepmc +1 more source
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen +11 more
wiley +1 more source
NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang +8 more
wiley +1 more source
THE RELATIONSHIP BETWEEN MATERNAL AGE AND PARITY ON THE INCIDENCE OF PREMATURE RUPTURE OF MEMBRANES
Wa Ode Sitti Fidia Husuni +2 more
openalex +2 more sources
GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton
Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang +7 more
wiley +1 more source
Age- and sex-specific deterioration on bone and osteocyte lacuno-canalicular network in a mouse model of premature aging. [PDF]
Yılmaz D +11 more
europepmc +2 more sources
Mechanistic insights into cadmium-related premature aging in <i>Drosophila</i> model. [PDF]
De Donno MD +5 more
europepmc +1 more source
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen +10 more
wiley +1 more source
Mitochondrial Respiratory Dysfunction Is Not Correlated With Mitochondrial Genotype in Premature Aging Mice. [PDF]
Tamashiro H +4 more
europepmc +1 more source
EditorialReducing premature mortality among youngand middle-aged adults
G. Ray Joel
openalex +1 more source

