Results 181 to 190 of about 214,960 (327)

Geroprotectors as a novel therapeutic strategy for COPD, an accelerating aging disease

International Journal of COPD, 2012
Kazuhiro Ito, Thomas Colley, Nicolas MercadoAirways Disease Section, National Heart and Lung Institute, Imperial College London, London, United KingdomAbstract: Chronic obstructive pulmonary disease (COPD) progresses very slowly and the majority of ...
Ito K, Colley T, Mercado N
doaj  

Ghrelin delays premature aging in Hutchinson-Gilford progeria syndrome. [PDF]

Aging Cell, 2023
Ferreira-Marques M, Carvalho A, Franco AC, Leal A, Botelho M, Carmo-Silva S, Águas R, Cortes L, Lucas V, Real AC, López-Otín C, Nissan X, de Almeida LP, Cavadas C, Aveleira CA.   +14 more
europepmc   +1 more source

Antro-pyloric canal values from early prematurity to full-term gestational age: An ultrasound study

, 2000
Abhinav Mathur
openalex   +1 more source

Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C

Advanced Science, EarlyView.
The release of COL6A3 by fibroblasts is sensed by the CD44 receptor on melanocytes, activating glutathione (GSH) metabolism and increasing melanocyte survival during skin organoid culture. SEMA3C released by bulge cells binds to the NRP1 receptor on melanocytes, regulating microtubule stability and promoting melanocyte recruitment and function during ...
Tingting Li, Xinzhu Li, Xiao Xiang, Jundong Huang, Xinyu Shen, Mengyue Wang, Jingwei Jiang, Shiwen Shao, Zeming Li, Tian Xie, Deming Liu, Yiping Zhao, Rui Ma, Wenyu Wu, Wei Shi, Cheng‐Ming Chuong, Ji Li, Mingxing Lei   +17 more
wiley   +1 more source

Excessive apoptosis of Rip1-deficient T cells leads to premature aging. [PDF]

EMBO Rep, 2023
Wang L, Zhang X, Zhang H, Lu K, Li M, Li X, Ou Y, Zhao X, Wu X, Wu X, Liu J, Xing M, Liu H, Zhang Y, Tan Y, Li F, Deng X, Deng J, Zhang X, Li J, Zhao Y, Ding Q, Wang H, Wang X, Luo Y, Zhou B, Zhang H.   +26 more
europepmc   +1 more source

Human Genome and Diseases: A new series of reviews in CMLS Werner Syndrome: genetic and molecular basis of a premature aging disorder

, 2001
Michel Lebel
openalex   +1 more source

Human premature aging, DNA repair and RecQ helicases [PDF]

, 2007
Robert Brosh, Vilhelm A. Bohr
openalex   +1 more source

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc^−/− mice with short telomeres

, 2001
Enrique Samper, Juana M. Flores, Marı́a A. Blasco   +2 more
openalex   +2 more sources

Premature aging in mice activates a systemic metabolic response involving autophagy induction [PDF]

, 2008
Guillermo Mariño, Alejandro P. Ugalde, Natalia Salvador-Montoliu, Ignacio Varela, Pedro M. Quirós, Juan Cadiñanos, Ingrid van der Pluijm, José M.P. Freije, Carlos López-Otı́n   +8 more
openalex   +1 more source