Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects
Interdisciplinary Medicine, EarlyView.Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou +6 more
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Predictive Value of Neutrophils, Lymphocytes, Platelets, Neutrophil-Lymphocyte Ratio (NLR), and Platelets-Lymphocyte Ratio (PLR) in Preterm Labor: Single and Combined Indices. [PDF]
Obstet Gynecol IntElmaradny E +9 more
europepmc +1 more source
Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics
Interdisciplinary Medicine, EarlyView.This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li +7 more
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Effect of labor dance on induction duration, first-stage labor, and maternal anxiety in pregnant women with term premature rupture of membranes: A randomized controlled trial. [PDF]
Eur J MidwiferyZheng J, Wang B, Duan D, Wu Y, Yang L.
europepmc +1 more source
Correspondence (letter to the editor): Primary prevention of premature labor was given short shrift. [PDF]
Dtsch Arztebl Int, 2013 Conradt A.
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Irrigation and Drainage, EarlyView.ABSTRACT This study develops an integrated simulation–optimization framework for sustainable crop allocation and water resource management in the Bargarh Canal Command (BCC), eastern India. Efficient irrigation allocation remains a critical challenge due to competing demands, groundwater–surface water interactions and environmental constraints ...
Priyanka Mohapatra +2 more
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Magnitude and associated factors of premature rupture of membranes among pregnant women admitted to a university comprehensive specialized hospital in Central Ethiopia. [PDF]
BMC Pregnancy ChildbirthLorato SS +4 more
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International Studies of Economics, EarlyView.ABSTRACT In this article, we apply the notion of gravitational fields to commercial attraction, with the aim of providing valuable insights to inform the development of an econophysical methodology. We revisit the traditional notion of gravitational fields, extending it to encompass multiple economic variables and incorporating mobility and production ...
Luigi Capoani +3 more
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Prevalence and associated factors of meconium aspiration syndrome among neonates admitted to Neonatal Intensive Care Units in Public Hospitals of Harari Region, Eastern Ethiopia. [PDF]
PLoS OneAman J +6 more
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Journal of Addictions &Offender Counseling, EarlyView.ABSTRACT This article examines the current landscape of clinical supervision in addiction treatment and proposes a blended supervision framework integrating developmental, competency‐based, and trauma‐informed approaches. The article explores how this integrated model can enhance clinical competence, ethical practice, and counselor resilience while ...
Cyrus Williams +2 more
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